S. Parrish

Publications13
h-index6
Citations104
Highly Influential Citations5
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Depsipeptides from a Guamanian Marine Cyanobacterium, Lyngbya bouillonii, with Selective Inhibition of Serine Proteases.
TLDR
Isolated from a Guamanian sample of Lyngbya bouillonii, the planar structures were elucidated on the basis of HR-ESI-MS and NMR data, while the absolute configurations were determined by employing functional group conversions, modified Marfey's analysis, and detailed analyses of ROESY correlations.
Spongiapyridine and Related Spongians Isolated from an Indonesian Spongia sp.
TLDR
Norditerpene 2 modestly inhibited aromatase with an IC50 of 34 μM and induced quinone reductase 1 activity with a CD (the concentration needed to double the enzymatic response) of 11.2 μM, and Diterpenes 3 is unusual, as the D-ring is a pyridyl ring system rather than the standard δ-lactone.
Isoflavonoids from Ficus benjamina and their inhibitory activity on BACE1.
TLDR
The structures of the eight new compounds were elucidated on the basis of extensive NMR experiments and mass spectrometric measurements and the inhibitory activity of the compounds on the proteolytic cleavage of amyloid precursor protein by the aspartic protease BACE1 was evaluated.
Bromotyrosine-derived metabolites from an Indonesian marine sponge in the family Aplysinellidae (Order Verongiida).
Seven new bromotyrosine-derived metabolites, purpuramine M-N (1-2), araplysillin VII-XI (3-7) and six known compounds (8-13) were isolated from an Indonesian sponge belonging to the family…
Ulapualides C-E Isolated from a Hawaiian Hexabranchus sanguineus Egg Mass.
TLDR
Three new ulapualides (3-5) were isolated from egg masses of the nudibranch Hexabranchus sanguineus and demonstrated submicromolar cytotoxicity against select NCI cell lines and most potent activity against MDA-MB-231 cells.
Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge Dactylospongia elegans
Several known sesquiterpenoid quinones and quinols (1–9), and kauamide (10), a new polyketide-peptide containing an 11-membered heterocycle, were isolated from the extracts of the Hawaiian marine…
Myrmenaphthol A, Isolated from a Hawaiian Sponge of the Genus Myrmekioderma.
TLDR
Neither 2 nor the structurally related 1 showed any activity against estrogen receptors at the concentrations tested, and a comparison of the experimental and predicted electronic circular dichroism spectra of 1 assigned an S configuration to the lone stereocenter.
New diterpene isolated from a sponge of genus Strongylophora.
Corrigendum to “Depsipeptides from a Guamanian Marine Cyanobacterium, Lyngbya bouillonii, with Selective Inhibition of Serine Proteases” [Tetrahedron Letters 51 (2010) 6718–6721]
Metabolites isolated from moorea producens, nostoc sphaericum, and spongia sp.
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