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Pharmacokinetics of a florfenicol-tylosin combination after intravenous and intramuscular administration to beagle dogs.
- E. Kim, E. Gebru, Joong-su Lee, J. Kim, S. Park
- Medicine, Chemistry
- The Journal of veterinary medical science
- 1 April 2011
A pharmacokinetic study of a commercial florfenicol-tylosin (2:1) combination product was conducted in six beagle dogs after intravenous (IV) and intramuscular (IM) administration at doses of 10… Expand
Acoustic characters and distribution pattern of modern fine-grained deposits in a tide-dominated coastal bay: Jinhae Bay, Southeast Korea
Jinhae Bay, a semi-enclosed, tide-dominated coastal embayment on the southeastern coast of Korea, receives large amounts of sediment derived from the Nakdong River. The irregular surface of the… Expand
Melatonin attenuates gentamicin-induced nephrotoxicity and oxidative stress in rats
The present study investigated the protective effects of melatonin (MT) against gentamicin (GM)-induced nephrotoxicity and oxidative stress in rats. We also investigated the effects of MT on… Expand
Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators…
Quercetin is a major bioflavonoid widely present in fruits and vegetables. It exhibits anti-inflammatory, anti-tumor, antioxidant properties and reduces cardiovascular disease risks. However, the… Expand
Protective effects of Pycnogenol on carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats.
- Young-Su Yang, Tai-Hwan Ahn, +6 authors J. Kim
- Chemistry, Medicine
- Food and chemical toxicology : an international…
Oxidative damage is implicated in the pathogenesis of various liver injuries. In the present study the ability of Pycnogenol (PYC) as an antioxidant to protect against CCl4-induced oxidative stress… Expand
Maternal exposure to multi-wall carbon nanotubes does not induce embryo-fetal developmental toxicity in rats.
- Jeong-Hyeon Lim, S. Kim, +6 authors J. Kim
- Birth defects research. Part B, Developmental and…
- 1 February 2011
BACKGROUND Although the potential risk of carbon nanotubes (CNTs) to humans has recently increased due to expanding production and widespread use, the potential adverse effects of CNTs on… Expand
Extracts ofPhellinus gilvus andPhellinus baumii inhibit pulmonary inflammation induced by lipopolysaccharide in rats
Compared to saline-challenged rats, rats exposed to 50 μg intratracheal lipopolysaccharide showed an increase of total white cells (from 0.3 x 106 to 2.4 × 106), neutrophils (from 0.09 × 106 to 1.8 ×… Expand
Pharmacokinetics and pharmacokinetic/pharmacodynamic integration of marbofloxacin after intravenous and intramuscular administration in beagle dogs
- S. Yohannes, E. Awji, S. Lee, S. Park
- Xenobiotica; the fate of foreign compounds in…
- 26 February 2015
Abstract 1. The aim of the present study was to determine the PKs of marbofloxacin in beagle dogs after intravenous (i.v.) and intramuscular (i.m.) administration, the ex vivo and in vitro PK/PD… Expand
Lipopolysaccharide-binding and neutralizing activities of surfactin C in experimental models of septic shock.
- Y. Hwang, B. Park, +4 authors H. Yun
- Biology, Medicine
- European journal of pharmacology
- 5 February 2007
To evaluate the anti-endotoxin activity of surfactin C, we studied its lipopolysaccharide-binding activity in vitro and therapeutic efficacy in experimental models of gram-negative septic shock. The… Expand
Effects of melamine on pregnant dams and embryo‐fetal development in rats
There are worldwide concerns regarding the potential adverse effect of melamine. This study investigated the potential effects of melamine on pregnant dams and embryo‐fetal development in… Expand