• Publications
  • Influence
Myocardial localization of coronavirus in COVID‐19 cardiogenic shock
We describe the first case of acute cardiac injury directly linked to myocardial localization of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in a 69‐year‐old patient with flu‐likeExpand
  • 266
  • 14
Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients
BackgroundDirect-acting antiviral (DAA) agents target HCV proteins; some of these have already been approved for the treatment of HCV infection, while others are in development. However, selection ofExpand
  • 83
  • 10
Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients
BackgroundProtease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development.ResultsThe aims of this study were to illustrate naturalExpand
  • 74
  • 8
Detection and pathogenicity of human metapneumovirus respiratory infection in pediatric Italian patients during a winter–spring season
Abstract Background Some diagnostic, epidemiological and clinical features of the recently discovered human metapneumovirus remainExpand
  • 61
  • 6
Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection.
Down-regulation of the initial burst of viremia during primary HIV infection is thought to be mediated predominantly by HIV-specific cytotoxic T lymphocytes, and the appearance of this response isExpand
  • 218
  • 5
Genotypic/phenotypic patterns of HIV-1 integrase resistance to raltegravir.
OBJECTIVES To understand the dynamic viral evolution observed during failure on raltegravir-containing regimens, we studied the genotypic and phenotypic patterns of resistance to raltegravir and theExpand
  • 51
  • 4
  • PDF
Monoclonal antibodies versus reverse transcription‐PCR for detection of respiratory viruses in a patient population with respiratory tract infections admitted to hospital
In the winter season 2001–2002, 239 nasopharyngeal aspirate and 15 bronchoalveolar lavage samples from 208 patients (135 pediatric and 73 adults, including 19 lung transplant recipients) admitted toExpand
  • 71
  • 4
Detection of a new HIV-1 reverse transcriptase mutation (Q145M) conferring resistance to nucleoside and non-nucleoside inhibitors in a patient failing highly active antiretroviral therapy.
The novel Q145M change was detected in HIV-1 reverse transcriptase (RT) of a patient failing highly active antiretroviral therapy (HAART). After Q145M insertion into a wild-type HIV-1 RT and theExpand
  • 20
  • 4
Quantitative molecular monitoring of human immunodeficiency virus type 1 activity during therapy with specific antiretroviral compounds.
Methods for the absolute quantitation of nucleic acids present in small amounts in biological samples (competitive PCR and competitive reverse transcription PCR) were applied to the direct monitoringExpand
  • 35
  • 3
  • PDF
CXCR4 and CCR5 Genetic Polymorphisms in Long-Term Nonprogressive Human Immunodeficiency Virus Infection: Lack of Association with Mutations other than CCR5-Δ32
ABSTRACT Polymorphisms in the coding sequences of CCR5 and CXCR4 were studied in a group of human immunodeficiency virus (HIV)-infected long-term nonprogressors. Two different point mutations wereExpand
  • 63
  • 3