• Publications
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Age of menopause and impact of climacteric symptoms by geographical region
TLDR
Regional differences in age at menopause and in climacteric symptoms are important to acknowledge and lay the foundation for an informed approach to the management of menopausal symptomatology and an understanding of its impact on women's health in the different regions of the world. Expand
Long-term treatment of uterine fibroids with ulipristal acetate ☆.
TLDR
Repeated 3-month UPA courses effectively control bleeding and shrink fibroids in patients with symptomatic fibroid problems, and NETA did not affect fibroid volume or endometrial histology. Expand
Denosumab Compared With Ibandronate in Postmenopausal Women Previously Treated With Bisphosphonate Therapy: A Randomized Open-Label Trial
TLDR
In postmenopausal women previously treated with a bisphosphonate and low BMD, denosumab treatment resulted in greater BMD increases than ibandronate at all measured sites. Expand
Safety of bazedoxifene in a randomized, double-blind, placebo- and active-controlled phase 3 study of postmenopausal women with osteoporosis
TLDR
Bazedoxifene showed a favorable safety and tolerability profile in women with postmenopausal osteoporosis and showed a neutral effect on the breast and an excellent endometrial safety profile. Expand
Prevalence and genotype distribution of human papillomavirus infection of the cervix in Spain: The CLEOPATRE study
TLDR
The high prevalence of HPV infection among young women may reflect recent changes in sexual behavior, and this study provides valuable baseline data for future assessment of the impact of current HPV vaccination programs in Spain. Expand
Epidemiology of risk factors and symptoms associated with menopause in Spanish women.
TLDR
Postmenopausal women presented significantly higher rates of menopausal symptoms when compared to perimenopausal women, and a high prevalence of risk factors for osteoporosis and cardiovascular disease was observed in this study. Expand
Menopausal hot flushes and night sweats: where are we now?
TLDR
Hot flushes are caused by changes in the central nervous system associated with estrogen withdrawal and are best treated with estrogen replacement therapy, and Objective monitoring of hot flushes indicates that placebo has little to no effect on their improvement. Expand
Hormonal changes during menopause.
TLDR
Ovarian senescence occurs gradually during the fourth and fifth decades of life, leading to menopause at an average age of about 51 years, with decreases in the levels of estrogens and androgens. Expand
Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixed-dose, randomized, double-blind trial.
TLDR
Clinical evidence is provided of the efficacy and safety of duloxetine at a fixed dose of 60 mg once daily in the treatment of chronic low back pain (CLBP) and some health outcomes. Expand
Managing urogenital atrophy.
TLDR
Oestrogen given systemically or locally in all dosage regimens is effective, but topical vaginal application alone is preferred if systemic treatment is not needed and treatment is long term and may be required for many years. Expand
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