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Antioxidant activities of aqueous extracts of selected plants
Abstract The antioxidant properties of 25 edible tropical plants, expressed as Trolox equivalent antioxidant capacity (TEAC), were studied using DPPH (1,1-diphenyl-2-picrylhydrazyl free radical)Expand
Rapid screening and characterisation of antioxidants of Cosmos caudatus using liquid chromatography coupled with mass spectrometry.
TLDR
It was found that ulam raja had extremely high antioxidant capacity, which could be partly responsible for its ability to reduce oxidative stress. Expand
Sensitive and rapid method to quantify icaritin and desmethylicaritin in human serum using gas chromatography-mass spectrometry.
TLDR
A sensitive method is developed and validated to quantify serum levels of icaritin and desmethylicarit in human sera, using gas chromatography-mass spectrometry for pharmacokinetic studies. Expand
Pharmacokinetics of prenylflavonoids and correlations with the dynamics of estrogen action in sera following ingestion of a standardized Epimedium extract.
TLDR
The pharmacokinetics of prenylflavonoids are correlated with the dynamics of their estrogenic effects and the potential estrogenicity of this Epimedium extract is revealed, which may aid the development of preNYlflav onoids as drugs for menopause and other conditions requiring estrogenic action. Expand
Simple and sensitive liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of five Epimedium prenylflavonoids in rat sera.
TLDR
This method was successfully applied to quantify levels of icariin, icariside I, icarside II, icaritin and desmethylicaritIn in rat sera after oral administration of an Epimedium preparation. Expand
A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein.
TLDR
The data support the feasibility for the development of dual agonists like icaritin, which are estrogenic but yet, through activating AhR-signaling, can destabilize ERα protein to restrict ERα-positive breast cancer cell growth. Expand
Characterization of antioxidants and change of antioxidant levels during storage of Manilkara zapota L.
TLDR
The best time for one to consume ciku king fruits at a flavorful stage with high amounts of antioxidants with AEAC values ranging from 600 to 1200 mg per 100 g fresh sample is suggested. Expand
Ultrasensitive cell-based bioassay for the measurement of global estrogenic activity of flavonoid mixtures revealing additive, restrictive, and enhanced actions in binary and higher order
TLDR
An assay reveals superagonistic, additive, and antagonistic ERalpha or ERbeta actions of flavonoids and adds to the understanding of the estrogenic effects of phytoestrogens in complex mixtures. Expand