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Assessment of five soil DNA extraction methods and a rapid laboratory-developed method for quality soil DNA extraction for 16S rDNA-based amplification and library construction.
Optimization of Nutrient Requirements and Culture Conditions for the Production of Rhamnolipid from Pseudomonas aeruginosa (MTCC 7815) using Mesua ferrea Seed Oil
The study observes that micronutrients play a significant role in rhamnolipid production from Pseudomonas aeruginosa and this methodology could be used to optimize the nutrients requirements and culture conditions to assist in bioremediation of crude oil contaminated ecosystems.
Computational Investigation of Zerumbone as an Inhibitor of TNF-alpha Using Molecular Dynamics and Molecular Docking Methods
- S. P. Singh, Khumukcham Nongalleima, N. I. Singh, W. K. Chanu, T. R. Singh, C. B. Singh
- Biology, Chemistry
- 10 November 2020
It was observed and substantiated that the α,β-Unsaturated carbonyl scaffold is the main driving force for anti-cancer activity of zerumbone and inhibition of TNF-α.
Metagenomics: An Application Based Perspective
Besides the application of metagenomics for unlocking novel biocatalysts from nature, it also has found applications in fields as diverse as bioremediation, personalized medicine, xenobiotic metabolism, and so forth.
Biodiesel derived waste glycerol as an economic substrate for biosurfactant production using indigenous Pseudomonas aeruginosa
The results suggest that the biosurfactant produced by the bacterium on waste glycerol may have potential application in hydrocarbon bioremediation.
Synthesis, anti-inflammatory evaluation and in silico studies of naphtho[1,2-e][1,3]oxazine derivatives as potential non-steroidal anti-inflammatory agents
- L. V. Chanu, Khumukcham Nongalleima, S. P. Singh, W. K. Chanu, C. B. Singh, O. Singh
- ChemistryMedicinal Chemistry Research
- 11 December 2019
A small molecule library of trans-1,3-diaryl-1H-naphtho[1,2-e][1,3]oxazines 4 is synthesised through multicomponent reactions involving aliphatic amines, aromatic aldehydes and β-naphthol using a…
Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa Biofilm and Virulence by Active Fraction of Syzygium cumini (L.) Skeels Leaf Extract: In-Vitro and In Silico Studies
The in vitro biofilm inhibition, virulence factor inhibition and the mode of interaction of bioactive components in Syzygium cumini with QS proteins of bacteria reported in this study might be an affordable and effective alternative method of controlling quorum sensing/biofilm-associated infections.
Valorization and Miscellaneous Prospects of Waste Musa balbisiana Colla Pseudostem
Resourceful utilization of the enormous quantum of agrowastes generated via agricultural practices can be supportive in waste management, environmental upgradation, and subsequent material and energy…
Molecular docking studies of quercetin and its analogues against human inducible nitric oxide synthase
Ten analogues of quercetin were found to be docked at the active site cavity with favorable ligand-protein molecular interaction and interestingly from the ADME-Toxicity analysis these analogues have enhanced pharmacological properties than quercETin.
Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha
The study shows that with the increasing concentration of zerumbone, there was a reduction of HCT116 cells proliferation based on the cell line study and hence higher TNF-alpha inhibitionbased on the T NF-alpha assay.