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Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ‐t) gene: expression in haploid germ cells and polyamine‐induced frameshifting
Polyamines are known to play important roles in the proliferation and differentiation of many types of cells. However, in the testis, where polyamines such as spermidine and spermine exist in highExpand
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Cancer induction by an organic arsenic compound, dimethylarsinic acid (cacodylic acid), in F344/DuCrj rats after pretreatment with five carcinogens.
Arsenic (As) is environmentally ubiquitous and an epidemiologically significant chemical related to certain human cancers. Dimethylarsinic acid (cacodylic acid; DMA) is one of the major methylatedExpand
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Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells.
Impaired bone formation resulting from a decline of osteoblast activity has been implicated in the pathogenesis of diabetic osteopenia. We examined the effects of high glucose concentration alone,Expand
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Identification of antimutagenic substances in an extract of edible red alga, Porphyra tenera (Asakusa-nori)
Recently, a relatively strong antimutagenic activity has been detected in the extract of Porphyra tenera (Asakusa-nori in Japanese) which showed a suppressive effect on mutagen-induced umu C geneExpand
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Identification of the four species of human malaria parasites by nested PCR that targets variant sequences in the small subunit rRNA gene
Abstract A polymorphic region of the small subunit rRNA gene of the four human malaria parasite species was sequenced to see intraspecies variations. Two new variant sequences were found in P. ovaleExpand
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The distribution and content of ubiquinone in foods.
We measured ubiquinone (UQ)-9 and UQ-10 content in various foods using high performance liquid chromatography. UQ-9 was detected in cereals, some vegetables and their products. Corn oil and wheatExpand
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Novel prenyltransferase gene encoding farnesylgeranyl diphosphate synthase from a hyperthermophilic archaeon, Aeropyrum pernix. Molecularevolution with alteration in product specificity.
Prenyltransferases catalyse sequential condensations of isopentenyl diphosphate with allylic diphosphates. Previously, we reported the presence of farnesylgeranyl diphosphate (FGPP) synthase activityExpand
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Using DNA-tagged mutagenesis to improve heterologous protein production in Aspergillus oryzae.
Using DNA-tagged mutagenesis to improve heterologous protein production in Aspergillus oryzae. Fungal Genetics and Biology 29, 28-37. Restriction enzyme-mediated integration (REMI) has been employedExpand
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Thrombopoietin inhibits in vitro osteoclastogenesis from murine bone marrow cells.
To determine whether thrombopoietin (TPO) can modulate the osteoclastic differentiation from hematopoietic stem cells, we investigated the effect of TPO on in vitro osteoclastogenesis by using theExpand
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PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.
Peroxisome proliferator-activated receptor gamma (PPAR-gamma), a member of the nuclear hormone receptor superfamily, is involved in suppression of growth of several types of tumors such asExpand
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