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The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum.
Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin).
- S. Osaki
- ChemistryThe Journal of biological chemistry
- 10 November 1966
A micromethod for the determination of ferroxidase (ceruloplasmin) in human serums.
A sensitive method for the detection of ceruloplasmin (ferroxidase) in human serums, using Fe(II) as the substrate, is described andvantages over other methods employing p-phenylenediamine as a substrate and the standardization of enzyme activity in terms of international enzyme units are discussed.
Mobilization of liver iron by ferroxidase (ceruloplasmin).
It is deduced that the elimination of free iron in the perfusate by ferroxidase would generate a very steep concentration gradient between iron storage cells and the capillary system, which would promote a rapid iron out-flux from the cells by diffusion.
Copper proteins and oxygen. Correlations between structure and function of the copper oxidases.
A comprehensive survey of the interaction of the copper proteins and oxygen is presented including a correlation of structure, function, and other properties of the known copper oxidases and of…
Role of iron in the oxidase activity of ceruloplasmin.
The release of iron from horse spleen ferritin by reduced flavins.
Ferritin-Fe(III) was rapidly and quantitatively reduced and liberated as Fe(II) by FMNH(2), FADH(2) and reduced riboflavin and gave complex second-order kinetics with overlapping fast and slow reactions.
Controlled Drug Release through a Plasma Polymerized Tetramethylcyclo-tetrasiloxane Coating Barrier
- S. Osaki, Meng Chen, P. Zamora
- Materials Science, BiologyJournal of biomaterials science. Polymer edition
- 1 January 2012
The experimental results indicate that plasma polymerizedTMCTS can be used as an over-coating to control drug elution at the desired release rate and the in vitro cytotoxicity test result suggested that the TMCTS plasma coatings did not produce a cytotoxic response to mammalian cells.
Investigation on Caeruloplasmin. II:Crystallization of Porcine Caeruloplasmin