• Publications
  • Influence
Potential for neural regeneration after neurotoxic injury in the adult mammalian retina.
It has long been believed that the retina of mature mammals is incapable of regeneration. In this study, using the N-methyl-D-aspartate neurotoxicity model of adult rat retina, we observed that someExpand
Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals
Regeneration in the mammalian CNS is severely limited. Unlike in the chick, current models hold that retinal neurons are never regenerated. Previously we demonstrated that, in the adult mammalianExpand
Macular choroidal thickness and volume in normal subjects measured by swept-source optical coherence tomography.
PURPOSE To study the choroidal thickness in healthy subjects by swept-source optical coherence tomography (SS-OCT) at longer wavelength. METHODS The macular area of 31 eyes (31 healthy volunteers)Expand
Purpose: To identify reticular pseudodrusen (RPD) in age-related macular degeneration using multiple imaging modalities, including the blue channel image of fundus photography, infrared reflectanceExpand
Three-dimensional profile of macular retinal thickness in normal Japanese eyes.
PURPOSE To demonstrate the three-dimensional macular thickness distribution in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate its association with sex, age, andExpand
In vitro and in vivo characterization of pigment epithelial cells differentiated from primate embryonic stem cells.
PURPOSE To determine whether primate embryonic stem (ES) cell-derived pigment epithelial cells (ESPEs) have the properties and functions of retinal pigment epithelial (RPE) cells in vitro and inExpand
Assessment of macular choroidal thickness by optical coherence tomography and angiographic changes in central serous chorioretinopathy.
OBJECTIVE To investigate the relationship between macular choroidal thickness measured by high-penetrating swept-source optical coherence tomography (SS-OCT) and angiographic findings in centralExpand
Factors associated with the response of age-related macular degeneration to intravitreal ranibizumab treatment.
PURPOSE To investigate factors affecting patient response to intravitreal ranibizumab treatment for age-related macular degeneration (AMD). DESIGN Retrospective chart review. METHODS We reviewedExpand
Subretinal drusenoid deposits AKA pseudodrusen.
A distinction between conventional drusen and pseudodrusen was first made in 1990, and more recently knowledge of pseudodrusen, more accurately called subretinal drusenoid deposits (SDDs), hasExpand
Effects of age, sex, and axial length on the three-dimensional profile of normal macular layer structures.
PURPOSE To identify sex-related differences and age-related changes in individual retinal layer thicknesses in a population of healthy eyes across the lifespan, using spectral domain opticalExpand