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- Publications
- Influence
Long non-coding RNAs in ovarian cancer: expression profile and functional spectrum
- S. Oncul, Paola Amero, C. Rodriguez-Aguayo, G. Calin, A. Sood, G. López-Berestein
- Medicine, Biology
- RNA biology
- 17 December 2019
ABSTRACT Long non-coding RNAs (lncRNAs), initially recognized as byproducts of the transcription process, have been proven to play crucial modulatory roles in preserving overall homoeostasis of cells… Expand
Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells.
- G. Karakaya, A. Ercan, S. Oncul, M. Aytemir
- Chemistry, Medicine
- Anti-cancer agents in medicinal chemistry
- 28 February 2019
BACKGROUND
Malignant melanoma is an agressive tumour related to the overproduction of melanin, which provides colors of skin, eyes and hair. In addition contributing to the risk of malignant… Expand
Discrimination of the Effects of Doxorubicin on Two Different Breast Cancer Cell Lines on Account of Multidrug Resistance and Apoptosis
Breast cancer is one of the most common cancer types and malfunctioning proteins in apoptotic pathways are known to be the main contributors of cancer development. In this study MCF-7 and MDA-MB-231… Expand
The interaction between the complement system and hemostatic factors.
- S. Oncul, V. Afshar-Kharghan
- Medicine
- Current opinion in hematology
- 20 July 2020
PURPOSE OF REVIEW
To discuss the crosstalk between the complement system and hemostatic factors (coagulation cascade, platelet, endothelium, and Von Willebrand Factor), and the consequences of this… Expand
A kojic acid derivative promotes intrinsic apoptotic pathway of hepatocellular carcinoma cells without incurring drug resistance
- S. Oncul, G. Karakaya, Mutlu Dilsiz Aytemir, A. Ercan
- Chemistry, Medicine
- Chemical biology & drug design
- 8 September 2019
Hepatocellular carcinoma is one of the most pervasive cancers with low prognosis, high frequency of recurrence, and metastasis. Studies conducted have focused on extricating novel strategies for… Expand