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Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma.
- M. Lee, Soyoung Kim, Ok-Kyoung Kwon, S. Oh, H. Lee, Kyungseop Ahn
- International immunopharmacology
- 1 April 2009
Asthma is an inflammatory disease of the airways, and the current focus in managing asthma is the control of inflammation. Resveratrol (3,4,5-trihydroxystilbene) is a polyphenolic stilbene found in… Expand
Benzothiadiazole enhances the elicitation of rosmarinic acid production in a suspension culture of Agastache rugosa O. Kuntze
Callus and suspension cultures were established from the leaves of Agastache rugosa. The suspension cell growth was maximum at 15 days after inoculation. The cellular content of rosmarinic acid… Expand
Melatonin attenuates neutrophil inflammation and mucus secretion in cigarette smoke‐induced chronic obstructive pulmonary diseases via the suppression of Erk‐Sp1 signaling
The incidence of chronic obstructive pulmonary disease (COPD) has substantially increased in recent decade. Cigarette smoke (CS) is the most important risk factor in the development of COPD. In this… Expand
Isolation and anticomplement activity of compounds from Dendropanax morbifera.
- Bo-Young Park, B. Min, +5 authors H. Lee
- Chemistry, Medicine
- Journal of ethnopharmacology
- 1 February 2004
Dendropanax morbifera Leveille (Araliaceae) is used in Korea for a variety of disease, such as migraine headache and dysmenorrhea. A new polyacetylene (1) and six known compounds (2-7) were isolated… Expand
Anti-aromatase activity of phytochemicals in white button mushrooms (Agaricus bisporus).
White button mushrooms (Agaricus bisporous) are a potential breast cancer chemopreventive agent, as they suppress aromatase activity and estrogen biosynthesis. Therefore, we evaluated the activity of… Expand
Diallyl-disulfide, an organosulfur compound of garlic, attenuates airway inflammation via activation of the Nrf-2/HO-1 pathway and NF-kappaB suppression.
- I. Shin, Jumi Hong, +6 authors K. Ahn
- Chemistry, Medicine
- Food and chemical toxicology : an international…
- 1 December 2013
Diallyl disulfide (DADS) is a major organosulfur compound found in garlic oil that is widely used as a flavoring agent. In this study, we evaluated the effects of DADS on airway inflammation using an… Expand
Anti-inflammatory and anti-allergic effects of kefir in a mouse asthma model.
Kefir is a microbial symbiont mixture that produces jelly-like grains. As a widely used neutraceutical, however, the therapeutic applicability of kefir is not certain. In order to investigate the… Expand
Melatonin inhibits MUC5AC production via suppression of MAPK signaling in human airway epithelial cells
Mucus acts as a primary defense system in the airway against various stimuli. However, excess mucus production causes a reduction in lung function via limitation of the airflow in the airway of… Expand
Luteolin 8-C-β-fucopyranoside inhibits invasion and suppresses TPA-induced MMP-9 and IL-8 via ERK/AP-1 and ERK/NF-κB signaling in MCF-7 breast cancer cells.
Matrix metalloproteinase 9 (MMP-9) and interleukin-8 (IL-8) play major roles in tumor progression and invasion of breast cancer cells. The present study was undertaken to investigate the inhibitory… Expand
MS‐1020 is a novel small molecule that selectively inhibits JAK3 activity
In order to identify Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling inhibitors, a cell‐based high throughput screening was performed using a plant extract library… Expand