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Phylogeny and PCR–based classification of Wolbachia strains using wsp gene sequences
TLDR
A method based on the use of group–specificwsp PCR primers which will allow Wolbachia isolates to be typed without the need to clone and sequence individualWolbachia genes is presented, which should facilitate future studies investigating the distribution and biology of these bacteria. Expand
16S rRNA phylogenetic analysis of the bacterial endosymbionts associated with cytoplasmic incompatibility in insects.
TLDR
Initial screening of insects indicates that cytoplasmic incompatibility may be a more general phenomenon in insects than is currently recognized and Lack of congruence between the phylogeny of the symbionts and their insect hosts suggest that horizontal transfer of symbiont between insect species may occur. Expand
Phylogenomics of the Reproductive Parasite Wolbachia pipientis wMel: A Streamlined Genome Overrun by Mobile Genetic Elements
TLDR
Genetic analysis of the wMel genome further supports the hypothesis that mitochondria share a common ancestor with the α-Proteobacteria, but shows little support for the grouping of mitochondria with species in the order Rickettsiales. Expand
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
TLDR
It is suggested that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases. Expand
The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations
TLDR
The successful transinfection of A. aegypti with the avirulent wMel strain of Wolbachia, which induces the reproductive phenotype cytoplasmic incompatibility with minimal apparent fitness costs and high maternal transmission, providing optimal phenotypic effects for invasion is described. Expand
Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission
TLDR
This work describes how the wMel Wolbachia infection, introduced into the dengue vector Aedes aegypti from Drosophila melanogaster, successfully invaded two natural A. aagypti populations in Australia, reaching near-fixation in a few months following releases of wMel-infected A.A. ae Egyptian adults. Expand
Wolbachia and Virus Protection in Insects
TLDR
It is demonstrated that Drosophila melanogaster flies infected with Wolbachia are less susceptible to mortality induced by a range of RNA viruses and might be exploited in future strategies to reduce transmission of pathogens by insects. Expand
Cloning and characterization of a gene encoding the major surface protein of the bacterial endosymbiont Wolbachia pipientis.
TLDR
The purification of one of the most abundantly expressed Wolbachia proteins from infected Drosophila eggs is reported and the subsequent cloning and characterization of the gene (wsp) that encodes it, revealing a high level of variability that will be a very useful tool for Wolbachian strain typing and phylogenetic analysis. Expand
Variation in Antiviral Protection Mediated by Different Wolbachia Strains in Drosophila simulans
TLDR
Protection from virus-induced mortality was associated with a delay in virus accumulation, but some Wolbachia-infected flies were tolerant to high titres of DCV, indicating that Wolbachio-mediated antiviral protection is not ubiquitous. Expand
Stable Introduction of a Life-Shortening Wolbachia Infection into the Mosquito Aedes aegypti
TLDR
The data suggest that targeting mosquito age with inherited Wolbachia infections may be a viable strategy to reduce the transmission of pathogens such as dengue viruses. Expand
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