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A Molecular Phylogeny of Living Primates
Comparative genomic analyses of primates offer considerable potential to define and understand the processes that mold, shape, and transform the human genome. However, primate taxonomy is bothExpand
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Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
Natural killer (NK) cells provide defense in the early stages of the innate immune response against viral infections by producing cytokines and causing cytotoxicity. The killer immunoglobulin-likeExpand
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The Late Miocene Radiation of Modern Felidae: A Genetic Assessment
Modern felid species descend from relatively recent (<11 million years ago) divergence and speciation events that produced successful predatory carnivores worldwide but that have confounded taxonomicExpand
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Placental mammal diversification and the Cretaceous–Tertiary boundary
Competing hypotheses for the timing of the placental mammal radiation focus on whether extant placental orders originated and diversified before or after the Cretaceous-Tertiary (K/T) boundary.Expand
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Whole-genome analyses resolve early branches in the tree of life of modern birds
To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handleExpand
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HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection
Natural killer (NK) cells provide a central defense against viral infection by using inhibitory and activation receptors for major histocompatibility complex class I molecules as a means ofExpand
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A Molecular Phylogeny for Bats Illuminates Biogeography and the Fossil Record
Bats make up more than 20% of extant mammals, yet their evolutionary history is largely unknown because of a limited fossil record and conflicting or incomplete phylogenies. Here, we present a highlyExpand
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Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1
Allotypes of the natural killer (NK) cell receptor KIR3DL1 vary in both NK cell expression patterns and inhibitory capacity upon binding to their ligands, HLA-B Bw4 molecules, present on targetExpand
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Comparative genomics reveals insights into avian genome evolution and adaptation
Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian speciesExpand
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Trends in indigenous foodborne disease and deaths, England and Wales: 1992 to 2000
Background: Commitment to food safety is evidenced by high profile governmental initiatives around the globe. To measure progress towards targets, policy makers need to know the baseline from whichExpand
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