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- Publications
- Influence
Combination of virtual and experimental 2DE together with ESI LC‐MS/MS gives a clearer view about proteomes of human cells and plasma
- S. Naryzhny, V. Zgoda, +8 authors A. Archakov
- Chemistry, Medicine
- Electrophoresis
- 1 January 2016
Virtual and experimental 2DE coupled with ESI LC‐MS/MS was introduced to obtain better representation of the information about human proteome. The proteins from HEPG2 cells and human blood plasma… Expand
Chromosome 18 transcriptome profiling and targeted proteome mapping in depleted plasma, liver tissue and HepG2 cells.
- V. Zgoda, A. Kopylov, +25 authors A. Archakov
- Biology, Medicine
- Journal of proteome research
- 4 January 2013
The final goal of the Russian part of the Chromosome-centric Human Proteome Project (C-HPP) was established as the analysis of the chromosome 18 (Chr 18) protein complement in plasma, liver tissue… Expand
[ProteoСat: a tool for planning of proteomic experiments].
- Vladlen S. Skvortsov, N. Alekseychuk, +4 authors O. Tikhonova
- Medicine, Computer Science
- Biomeditsinskaia khimiia
- 1 November 2015
TLDR
Chromosome 18 transcriptoproteome of liver tissue and HepG2 cells and targeted proteome mapping in depleted plasma: update 2013.
- E. Ponomarenko, A. Kopylov, +28 authors A. Archakov
- Biology, Medicine
- Journal of proteome research
- 3 January 2014
We report the results obtained in 2012-2013 by the Russian Consortium for the Chromosome-centric Human Proteome Project (C-HPP). The main scope of this work was the transcriptome profiling of genes… Expand
Targeted Quantitative Screening of Chromosome 18 Encoded Proteome in Plasma Samples of Astronaut Candidates.
- A. Kopylov, E. Ilgisonis, +10 authors A. Archakov
- Biology, Medicine
- Journal of proteome research
- 22 August 2016
This work was aimed at estimating the concentrations of proteins encoded by human chromosome 18 (Chr 18) in plasma samples of 54 healthy male volunteers (aged 20-47). These young persons have been… Expand
[Quantitative proteomics of human blood exosomes].
- N. Shushkova, N. Vavilov, +4 authors V. Zgoda
- Chemistry, Medicine
- Biomeditsinskaia khimiia
- 2018
Exosomes are extracellular membrane vesicles secreted by cells into biological fluids. The outer membrane of exosomes protects their content from degradation and contains markers of the parent cell.… Expand
State of the Art of Chromosome 18-Centric HPP in 2016: Transcriptome and Proteome Profiling of Liver Tissue and HepG2 Cells.
- E. Poverennaya, A. Kopylov, +22 authors A. Archakov
- Biology, Medicine
- Journal of proteome research
- 29 August 2016
A gene-centric approach was applied for a large-scale study of expression products of a single chromosome. Transcriptome profiling of liver tissue and HepG2 cell line was independently performed… Expand
200+ Protein Concentrations in Healthy Human Blood Plasma: Targeted Quantitative SRM SIS Screening of Chromosomes 18, 13, Y, and the Mitochondrial Chromosome Encoded Proteome.
- A. Kopylov, E. Ponomarenko, +17 authors A. Archakov
- Biology, Medicine
- Journal of proteome research
- 27 November 2018
This work continues the series of the quantitative measurements of the proteins encoded by different chromosomes in the blood plasma of a healthy person. Selected Reaction Monitoring with Stable… Expand
Application of selected reaction monitoring and parallel reaction monitoring for investigation of HL-60 cell line differentiation
- S. Novikova, O. Tikhonova, L. Kurbatov, T. Farafonova, I. Vakhrushev, V. Zgoda
- Medicine, Chemistry
- European journal of mass spectrometry
- 1 August 2017
Targeted mass spectrometry represents a powerful tool for investigation of biological processes. The convenient approach of selected reaction monitoring using stable isotope-labeled peptide standard… Expand
[Comparative proteomic profiling of nuclear and cytosolic fractions from cell lines of different origin].
- I. Vakhrushev, S. Novikova, A. Tsvetkova, M. Pyatnitskiy, K. Yarygin
- Chemistry, Medicine
- Biomeditsinskaia khimiia
- 1 June 2018
Proteomic analysis of the nuclear fraction is of great importance, since many cellular processes are initiated in the nucleus. Refinement and choice of experimental procedures for cell lysate… Expand