S. Nissen

Publications803
h-index99
Citations62,063
Highly Influential Citations1,581
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Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes.
TLDR
Patients and providers should consider the potential for serious adverse cardiovascular effects of treatment with rosiglitazone for type 2 diabetes mellitus as well as the availability of outcome data for myocardial infarction and death from cardiovascular causes.
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Alogliptin after acute coronary syndrome in patients with type 2 diabetes.
TLDR
Among patients with type 2 diabetes who had had a recent acute coronary syndrome, the rates of major adverse cardiovascular events were not increased with the DPP-4 inhibitor alogliptin as compared with placebo.
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Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.
TLDR
In the time-to-event analysis, the rate of the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, orNonfatal stroke among patients with type 2 diabetes mellitus was lower with liraglutide than with placebo.
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Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial.
TLDR
A recombinant ApoA-I Milano/phospholipid complex administered intravenously for 5 doses at weekly intervals produced significant regression of coronary atherosclerosis as measured by IVUS, and results require confirmation in larger clinical trials with morbidity and mortality end points.
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Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes.
TLDR
Among obese patients with uncontrolled type 2 diabetes, 3 years of intensive medical therapy plus bariatric surgery resulted in glycemic control in significantly more patients than did medical therapy alone.
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Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.
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Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5‐Year Outcomes
TLDR
Five‐year outcome data showed that, among patients with type 2 diabetes and a BMI of 27 to 43, bariatric surgery plus intensive medical therapy was more effective thanintensive medical therapy alone in decreasing, or in some cases resolving, hyperglycemia.
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American College of Cardiology Clinical Expert Consensus Document on Standards for Acquisition, Measurement and Reporting of Intravascular Ultrasound Studies (IVUS). A report of the American College…
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Coronary Plaque Classification With Intravascular Ultrasound Radiofrequency Data Analysis
TLDR
Coronary plaque composition can be predicted through the use of IVUS radiofrequency data analysis, and autoregressive classification schemes performed better than classic Fourier methods, enabling in vivo plaque characterization.
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Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials.
TLDR
Pioglitazone is associated with a significantly lower risk of death, myocardial infarction, or stroke among a diverse population of patients with diabetes and is homogeneous across trials of different durations, for different comparators, and for patients with or without established vascular disease.
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