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Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness.
A mysterious respiratory illness with high mortality was recently reported in the southwestern United States. Serologic studies implicated the hantaviruses, rodent-borne RNA viruses usually… Expand
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
BackgroundSevere acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.ResultsWe report,… Expand
Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte… Expand
The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing.
- A. Sanchez, S. Trappier, B. Mahy, C. J. Peters, S. Nichol
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 16 April 1996
In late 1994 and early 1995, Ebola (EBO) virus dramatically reemerged in Africa, causing human disease in the Ivory Coast and Zaire. Analysis of the entire glycoprotein genes of these viruses and… Expand
Isolation of Genetically Diverse Marburg Viruses from Egyptian Fruit Bats
In July and September 2007, miners working in Kitaka Cave, Uganda, were diagnosed with Marburg hemorrhagic fever. The likely source of infection in the cave was Egyptian fruit bats (Rousettus… Expand
Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations
The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed several times since the discovery of its members, resulting in a plethora of species and virus names and… Expand
Discovery of Swine as a Host for the Reston ebolavirus
Not Reston at All Reston ebolavirus is named, mistakenly perhaps, for Reston, Virginia, where it was discovered in the 1970s in imported macaques. After some alarm it was found not to be virulent in… Expand
Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation.
Ebola virus (EBOV) infection blocks cellular production of alpha/beta interferon (IFN-alpha/beta) and the ability of cells to respond to IFN-alpha/beta or IFN-gamma. The EBOV VP35 protein has… Expand
Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus.
A peripheral membrane protein that is interactive with lymphocytic choriomeningitis virus (LCMV) was purified from cells permissive to infection. Tryptic peptides from this protein were determined to… Expand
A new phlebovirus associated with severe febrile illness in Missouri.
Two men from northwestern Missouri independently presented to a medical facility with fever, fatigue, diarrhea, thrombocytopenia, and leukopenia, and both had been bitten by ticks 5 to 7 days before… Expand