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Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber.
There is considerable interest in the discovery of hypocholesterolemic drugs whose mode of action is the inhibition of sterol biosynthesis. Culture broths of microorganisms have yielded activeExpand
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Characterization of the pigment produced by the planarian, Dugesia ryukyuensis.
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Stimulatory effects of neopterin on hematopoiesis in vitro are mediated by activation of stromal cell function.
The pteridine neopterin (NP) was shown to be produced by monocytes and is known to be a useful marker of immunological activation, although, its biological activity is still unclear. Recently, weExpand
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Larval arm resorption proceeds concomitantly with programmed cell death during metamorphosis of the sea urchin Hemicentrotus pulcherrimus
Sea urchins are excellent models to elucidate metamorphic phenomena of echinoderms. However, little attention has been paid to the way that their organ resorption is accomplished by programmed cellExpand
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Melanosome of toad: a storehouse of riboflavin.
Abstract Intercellular and subcellular distribution of riboflavin in the adult skin of a toad, Bufo bufo japonicus , was studied. Riboflavin was found always in association with dermal melanophores,Expand
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Morphological and biochemical characterization of the cream markings in the integument of the female isopod, Armadillidium vulgare.
Cream markings aligned along the dorsal region of the female isopod, A. vulgare, were investigated with light and a fluorescence microscope and an electron microscope. Biochemical studies were alsoExpand
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Effect of calcium antagonists on light response of cultured melanophors of Oryzias latipes
Dispersion of melanosomes in Oryzias melanophores, induced by illumination, was completely inhibited by the Ca2+ antagonists lanthanum (0.2 mM), verapamil (0.3 mM), and papaverine (0.3 mM), but onlyExpand
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Immunological dissimilarity in protein component (dynein 1) between outer and inner arms within sea urchin sperm axonemes
The 0.5 M KCl-treatment solubilizes the outer arms from sea urchin sperm axonemes. Approximately 30 percent of A-polypeptide, corresponding to dynein 1 in SDS- polyacrylamide gel, was solubilized byExpand
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Comparative study of eye defective worm 'menashi' and regenerating wild-type in planarian, Dugesia ryukyuensis.
Inbreeding of the sexualized planarian, Dugesia ryukyuensis, produces eye-defective worms, menashi, in the F1 population. To study the effects of this mutation on the eye, we observed the eye-regionExpand
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The effects of melanophore-stimulating hormone and cyclic nucleotides on teleost fish chromatophores.
Abstract The effects of melanophore-stimulating hormone (MSH) and cyclic nucleotides on pigment translocation within the isolated scale chromatophores of the medaka, Oryzias latipes , were examinedExpand
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