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RADICAL SCAVENGING ACTIVITIES AND NATURAL INDICATOR ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACT OF Rosa Damascena
Rosa damascena mill L. commonly known as rose having several pharmacological properties including anti-HIV, antibacterial, antioxidant, antitussive, hypnotic, anti-diabetic and relaxant effect on… Expand
Effects of various anti-inflammatory drugs on type II collagen-induced arthritis in rats.
The effects of some commonly used anti-inflammatory and anti-arthritic drugs on the inflammatory and immunological manifestations of type II collagen-induced arthritis in rats were studied. Among the… Expand
Synthesis of collagenase and neutral proteases by articular chondrocytes: stimulation by a macrophage-derived factor.
- K. Deshmukh-Phadke, M. Lawrence, S. Nanda
- Chemistry, Medicine
- Biochemical and biophysical research…
- 14 November 1978
Summary Rabbit peritoneal macrophages, when incubated in culture with bacterial lipopolysaccharides, release a factor which stimulates the production of collagenase and neutral proteases by chondro-… Expand
Effects of various inhibitors of arachidonic acid oxygenation on macrophage superoxide release and tumoricidal activity.
Macrophages release a variety of arachidonic acid metabolites after treatment with various membrane triggers or particulate stimuli. We examined the role of phospholipase and lipoxygenase inhibitors… Expand
Macrophage factor that induces neutral protease secretion by normal rabbit chondrocytes. Studies of some properties and effects on metabolism of chondrocytes.
- K. Deshmukh-Phadke, S. Nanda, K. Lee
- Chemistry, Medicine
- European journal of biochemistry
- 1 February 1980
Normal rabbit-articular chondrocytes secrete very small amounts of degradative enzymes in culture. Rabbit peritoneal macrophages, when activated with lipopolysaccharides, release a factor in the… Expand
Comparison of various assays to quantitate macrophage activation by biological response modifiers.
Macrophages treated with various compounds that enhance host antitumor resistance exhibit measurable changes in metabolism, function, and surface antigens. In this study, murine peptone-induced… Expand
Release of chondrocyte-stimulating factor by rabbit peritoneal macrophages.
- K. Phadke, S. Nanda, P. Marder, D. G. Carlson
- Biology, Medicine
- Clinical and experimental immunology
- 1 February 1981
Cultured rabbit peritoneal macrophages, after stimulation with lipopolysaccharides (LPS), produce a factor that induces normal rabbit articular cartilage cells (chondrocytes) to release collagenase… Expand
Release of proteases from cartilage cells as a result of activation by a macrophage factor--effects of some anti-inflammatory drugs.
Secretion of chondrocyte stimulating factor by macrophages as a result of activation with collagen and proteoglycans.
In this study, we have investigated the role of extracellular matrix components of connective tissue, collagen and proteoglycans, in the activation of rabbit macrophages and articular chondrocytes.… Expand
Effects of benoxaprofen on the inflammatory, humoral and cellular components of type II collagen-induced arthritis in rats.
The effects of benoxaprofen and some other anti-inflammatory drugs on the inflammatory, cellular, and humoral components of type II collagen-induced arthritis in rats were studied. At the given… Expand