S. Nagaoka

Publications61
h-index17
Citations1,105
Highly Influential Citations7
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Low-friction hydrophilic surface for medical devices.
A hydrophilic polymer surface was developed exhibiting excellent low frictional property, namely slipperiness, when in contact with water or physiological fluid due to the reaction of… Expand
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A new antithrombogenic material with long polyethyleneoxide chains.
The PVC-g-MnG polymers were synthesized by photo-induced graft copolymerization of methoxypoly (ethyleneoxide)monomethacrylate (MnG) with various chain lengths (n) of polyethyleneoxide (PEO) (n = 4,… Expand
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Biocompatibility of fluorinated polyimide.
Contact between blood and biomaterial triggers a complex series of events including protein adsorption, leukocyte adhesion and activation, and complement activation. In this article, a series of… Expand
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Selective cell death by water-soluble Fe-porphyrins with superoxide dismutase (SOD) activity.
We investigated the effect on cell death of reactive oxygen species induced by [[5,10 (or 5,15)-bis(N-methyl-4-pyridyl)-15,20 (or 10,20) diphenyl]porphinato]iron (cis-FeMPy(2)P(2)P or… Expand
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Superoxide dismutase as a target enzyme for Fe-porphyrin-induced cell death.
The cell viability of human cancer cell lines treated with [5,10-bis(N-methyl-4-pyridyl)-15,20-diphenyl]porphinatoiron(III) (cis-FeMPy(2)P(2)P) has been estimated. The cis-FeMPy(2)P(2)P is a… Expand
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Clinical application of antithrombogenic hydrogel with long poly(ethylene oxide) chains.
Thirty clinical tests on PVC drain tubes coated with hydrophilic copolymer with long poly(ethylene oxide) chains (PEO-COAT) were carried out. Controls were non-coated PVC drain tubes. Thrombogenesis… Expand
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The effect of releasing heparin from the heparinized hydrophilic polymer (HRSD) on the process of thrombus formation.
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Surface modification of poly(l-lactic acid) affects initial cell attachment, cell morphology, and cell growth
The object of this study was to develop a highly porous scaffold to be used in regeneration of blood vessels, nerves, and other hollow tissues with small openings. Using the phase-inversion method… Expand
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Three goats survived for 288 days, 243 days and 232 days with hybrid total artificial heart (HTAH).
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Design of manganese porphyrin modified with mitochondrial signal peptide for a new antioxidant.
A new design of antioxidant, consisting of manganese (Mn) porphyrin and signal peptide for mitochondrial targeting, is reported. The resulting Mn-porphyrin-oligopeptide conjugate exhibited… Expand
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