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Association Mapping: Critical Considerations Shift from Genotyping to Experimental Design
The goal of many plant scientists' research is to explain natural phenotypic variation in terms of simple changes in DNA sequence. Traditionally, linkage mapping has been the most commonly employedExpand
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Genetic structure and domestication history of the grape
The grape is one of the earliest domesticated fruit crops and, since antiquity, it has been widely cultivated and prized for its fruit and wine. Here, we characterize genome-wide patterns of geneticExpand
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How culture shaped the human genome: bringing genetics and the human sciences together
Researchers from diverse backgrounds are converging on the view that human evolution has been shaped by gene–culture interactions. Theoretical biologists have used population genetic models toExpand
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LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms
Obtaining genome-wide genotype data from a set of individuals is the first step in many genomic studies, including genome-wide association and genomic selection. All genotyping methods suffer fromExpand
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Genetic diversity and population structure assessed by SSR and SNP markers in a large germplasm collection of grape
BackgroundThe economic importance of grapevine has driven significant efforts in genomics to accelerate the exploitation of Vitis resources for development of new cultivars. However, although a largeExpand
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Rapid Genomic Characterization of the Genus Vitis
Next-generation sequencing technologies promise to dramatically accelerate the use of genetic information for crop improvement by facilitating the genetic mapping of agriculturally importantExpand
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Distinct Genetic Architectures for Male and Female Inflorescence Traits of Maize
We compared the genetic architecture of thirteen maize morphological traits in a large population of recombinant inbred lines. Four traits from the male inflorescence (tassel) and three traits fromExpand
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The Genetic Structure of Marijuana and Hemp
Despite its cultivation as a source of food, fibre and medicine, and its global status as the most used illicit drug, the genus Cannabis has an inconclusive taxonomic organization and evolutionaryExpand
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Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation
Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidateExpand
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Identifying genes underlying skin pigmentation differences among human populations
Skin pigmentation is a human phenotype that varies greatly among human populations and it has long been speculated that this variation is adaptive. We therefore expect the genes that contribute toExpand
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