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More of the Gut in the Lung: How Two Microbiomes Meet in ARDS
In critically ill patients, lung and gut microbiomes undergo profound changes. Lung microbiome might become enriched with gut-associated microbes as recently demonstrated in sepsis and acuteExpand
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HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease.
In Crohn's disease, pathogenic Th17-cells express low levels of CD39 ectonucleotidase and are refractory to the immunosuppressive effects of unconjugated bilirubin (UCB), an endogenous ligand forExpand
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Modulation of CD39 and exogenous APT102 correct immune dysfunction in experimental colitis and Crohn's disease.
BACKGROUND AND AIMS CD39/ENTPD1 scavenges pro-inflammatory nucleotides, to ultimately generate immunosuppressive adenosine, having a central role in immune-homeostasis. Global deletion of Cd39Expand
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Terminal solid solubility of hydrogen in Zr-alloy pressure tube materials
Abstract In this work, terminal solid solubility (TSS) of hydrogen for Zr-alloy pressure tube materials was determined corresponding to end of hydride dissolution (TSSD) and start of hydrideExpand
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Altered aryl-hydrocarbon-receptor signalling affects regulatory and effector cell immunity in autoimmune hepatitis.
BACKGROUND & AIMS In autoimmune hepatitis (AIH) imbalance between Treg and Th17-cells has been linked to low levels of CD39, an ectoenzyme that hydrolyses ATP ultimately generating immunosuppressiveExpand
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Pumping speed offered by activated carbon at liquid helium temperatures by sorbents adhered to indigenously developed hydroformed cryopanel
Towards the aim of developing a pump with large pumping speed of the order of 1 L/(s-cm2) or above for gases like hydrogen and helium through physical adsorption, development of activated carbonExpand
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Cryoadsorption cryopump with large pumping speeds application has been developed at the Institute for Plasma Research (IPR). These pumps are cooled with liquid helium for cryopumping panels belowExpand
Measurement of outgassing rate for GTAW welded SS304 materials
Outgassing plays an important role to achieve Ultra High Vacuum (UHV) and to maintaining the required vacuum level of the vessel. For a large size machines like Tokamak, accelerators, spaceExpand