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Pantoprazole infusion as adjuvant therapy to endoscopic treatment in patients with peptic ulcer bleeding: Prospective randomized controlled trial
Background and Aim:  Following successful endoscopic therapy in patients with peptic ulcer bleeding, rebleeding occurs in 20% of patients. Rebleeding remains the most important determinant of poorExpand
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‘Open access’ generic method for continuous determination of major human CYP450 probe substrates/metabolites and its application in drug metabolism studies
1. An ‘open access’ generic high-performance liquid chromatography method was developed for different combination sets each containing specific cytochrome P450 probe substrate and the correspondingExpand
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Pre-clinical assessment of DRF 4367, a novel COX-2 inhibitor: Evaluation of pharmacokinetics, absolute oral bioavailability and metabolism in mice and comparative inter-species in vitro metabolism
The aim of this study was to characterize the pharmacokinetics and determine the absolute bioavailability and metabolism of DRF 4367, a novel COX-2 inhibitor, in mice. In addition, the in vitroExpand
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Sudden Blindness in a 50-Year-Old Woman
A 50-year-old AfricanAmerican woman presented to the emergency department complaining of sudden-onset complete bilateral blindness. Past medical history was significant for hypertension and stage 4Expand