• Publications
  • Influence
Preliminary report on the International Conference for the Development of Standards for the Treatment of Anorectal Malformations.
TLDR
A new International diagnostic classification system, operative groupings and a method of postoperative assessment of continence was developed by consensus of a large contingent of participants experienced in the management of patients with ARM to allow for a common standardization of diagnosis and comparing postoperative results. Expand
The epidemiology of neonatal tumours
TLDR
Cytogenetics of neonatal neoplasms appear to differ from neoplasm in older children, thus possibly explaining some of the observed differences in clinical behaviour, and a number of examples are explored. Expand
The contribution of associated congenital anomalies in understanding Hirschsprung’s disease
  • S. Moore
  • Medicine
  • Pediatric Surgery International
  • 4 March 2006
TLDR
The importance of certain flanking genes of critical areas in the final phenotypic expression of HSCR are explored, appearing to arise from the combined cumulative effects of susceptibility loci at critical genes controlling the mechanisms of cell proliferation, differentiation and maturation. Expand
The peripheral anionic site of acetylcholinesterase: structure, functions and potential role in rational drug design.
TLDR
The structure and multiple functions of the peripheral anionic site of acetylcholinesterase are discussed, together with its potential as a target in rational drug design for the development of novel and improved inhibitors and of therapeutics for the treatment of neural cancers, nerve regeneration and neurodegenerative disorders such as Alzheimer's disease. Expand
Diagnostic aspects of cervical lymphadenopathy in children in the developing world: a study of 1,877 surgical specimens
TLDR
The incidence of serious pathology in more than one-half of the cervical LNs examined justifies aggressive surgical investigation, anddiagnostically difficult subgroup requiring further investigation. Expand
Total colonic aganglionosis and Hirschsprung’s disease: a review
  • S. Moore
  • Medicine
  • Pediatric Surgery International
  • 2014
TLDR
This study reviews what isknown about the clinical, radiological and histopathologic differences between TCA and the more frequently encountered recto-sigmoid and correlates them with what is currently known about the genetic and molecular biologic background to find possible pathogenetic mechanisms. Expand
Retrospective surveillance of intussusception in South Africa, 1998-2003.
TLDR
Intussusception appears to be a relatively frequent occurrence in children in South Africa, and although the clinical spectrum appears to vary, there is an apparent link to intestinal infection, which requires further investigation. Expand
Why has butyrylcholinesterase been retained? Structural and functional diversification in a duplicated gene
TLDR
The structure of butyrylcholinesterase's catalytic apparatus is a compromise between the apparently conflicting selective demands of a more generalised detoxifier and the necessity for maintaining high catalytic efficiency. Expand
Hepatocellular carcinoma in children
TLDR
Six children with HCC treated by the paediatric oncology unit at Tygerberg Hospital in Cape Town over an 8-year period are reviewed, with one patient surviving for more than 75 months following surgical resection and remains well. Expand
Hirschsprung disease: current perspectives
TLDR
This work is licensed under the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3. 0/). Expand
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