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Verbal Working Memory Load Affects Regional Brain Activation as Measured by PET
The data support a model of working memory that includes both storage and executive processes that recruit a network of brain areas, all of which are involved in task performance.
Spatial working memory in humans as revealed by PET
P positron emission tomography studies of regional cerebral blood flow in normal humans that reveal activation in right-hemisphere prefrontal, occipital, parietal and premotor cortices accompanying spatial working memory processes begin to uncover the circuitry of a working memory system in humans.
Spatial versus Object Working Memory: PET Investigations
The results of the three experiments clearly imply that different working-memory buffers are used for storing spatial and object information.
A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET.
3D-SSP enables quantitative data extraction and reliable localization of metabolic abnormalities by means of stereotactic coordinates and is a promising approach for interpreting functional brain PET scans.
FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease.
Visual interpretation of FDG-PET after brief training is more reliable and accurate in distinguishing FTD from AD than clinical methods alone and adds important information that appropriately increases diagnostic confidence, even among experienced dementia specialists.
Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias
Standardized automated analysis of 18F-FDG PET scans may provide an objective and sensitive support to the clinical diagnosis in early dementia.
Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial.
These results support longer trials of intranasal insulin therapy for patients with amnestic mild cognitive impairment and patients with AD.
Brain activation in PTSD in response to trauma-related stimuli
Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study
A newly emerging reduction of rCMRglc in prefrontal cortical areas is associated with the transition from MCI to AD, and this change was observed in the MCIMCI group.
Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain.
PET was used to detect increases in regional cerebral blood flow in normal humans as they discriminated differences in the intensity of noxious and innocuous thermal stimulation applied to the nondominant (left) arm and significant increases in rCBF were seen in the contralateral sensorimotor cortex and lenticular nucleus.