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Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network.
OBJECTIVE DSM-5 introduced the "with mixed features" specifier for major depressive episodes. The authors assessed the prevalence and phenomenology of mixed depression among bipolar disorder patientsExpand
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Childhood-compared to adolescent-onset bipolar disorder has more statistically significant clinical correlates.
BACKGROUND The strengths and limitations of considering childhood-and adolescent-onset bipolar disorder (BD) separately versus together remain to be established. We assessed this issue. METHODS BDExpand
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Trends in pharmacotherapy in patients referred to a bipolar specialty clinic, 2000-2011.
OBJECTIVE To assess mood stabilizer (MS) and second-generation antipsychotic (SGA) prescribing trends in bipolar disorder (BD) outpatients referred to a bipolar disorder specialty clinic over theExpand
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The prevalence and burden of bipolar depression.
BACKGROUND Bipolar disorder is characterized by debilitating episodes of depression and mood elevation (mania or hypomania). For most patients, depressive symptoms are more pervasive than moodExpand
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Treatment of bipolar disorder: Review of evidence regarding quetiapine and lithium.
BACKGROUND Lithium, the prototypical mood stabilizer, and quetiapine, a second-generation antipsychotic, are widely used acute and maintenance pharmacotherapies for bipolar disorder. The Clinical andExpand
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Brain-derived neurotrophic factor val66met genotype and early life stress effects upon bipolar course.
BACKGROUND Gene-environment interactions may contribute to bipolar disorder (BD) clinical course variability. We examined effects of brain-derived neurotrophic factor (BDNF) val66met genotype andExpand
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Different characteristics associated with suicide attempts among bipolar I versus bipolar II disorder patients.
BACKGROUND Suicide attempts are common in patients with bipolar disorder (BD), and consistently associated with female gender and certain unfavorable BD illness characteristics. Findings vary,Expand
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Age at onset in patients with bipolar I and II disorder: a comparison of large sample studies.
BACKGROUND Bipolar Disorder (BD) is a leading cause of disability worldwide and factors contributing to its burden include chronic relapsing course, comorbidity, suicide risk, and early age at onsetExpand
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More inclusive bipolar mixed depression definition by permitting overlapping and non‐overlapping mood elevation symptoms
The objective of this study was to assess the strengths and limitations of a mixed bipolar depression definition made more inclusive than that of the Diagnostic and Statistical Manual of MentalExpand
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