Comparative trends in shortening velocity and force production in skeletal muscles.
- S. Medler
- BiologyAmerican Journal of Physiology. Regulatory…
- 1 August 2002
Overall, the contractile properties of skeletal muscles are conserved among phylogenic groups, but have been significantly influenced by other factors such as body size and mode of locomotion.
Myofibrillar protein isoform expression is correlated with synaptic efficacy in slow fibres of the claw and leg opener muscles of crayfish and lobster.
- D. Mykles, S. Medler, A. Koenders, R. Cooper
- BiologyJournal of Experimental Biology
- 15 February 2002
The correlation between slow fibre phenotype and strength of innervation suggests a relationship between synaptic structure and expression of troponin isoforms.
Skeletal muscle fiber types in the ghost crab, Ocypode quadrata: implications for running performance
This study investigated skeletal muscle fiber types comprising the extensor and flexor carpopodite muscles in relation to running performance in the ghost crab and proposed that these muscles are functionally divided into a two-geared system, with the aerobic fibers used for slow sustained activities and the glycolytic mid-region fibers being reserved for explosive sprints.
Myostatin from the American lobster, Homarus americanus: Cloning and effects of molting on expression in skeletal muscles.
- K. MacLea, J. A. Covi, D. Mykles
- BiologyComparative biochemistry and physiology. Part A…
- 1 December 2010
Analysis of myofibrillar proteins and transcripts in adult skeletal muscles of the American lobster Homarus americanus: variable expression of myosins, actin and troponins in fast, slow-twitch and…
Overall, these patterns demonstrate that crustacean skeletal muscles cannot be strictly categorized into discrete fiber types, but a muscle's properties probably represent a point on a continuum of fiber types.
Diet‐induced obesity alters skeletal muscle fiber types of male but not female mice
- Maxwell S Denies, Jordan Johnson, S. Medler
- BiologyPhysiological Reports
- 1 January 2014
The reported trends indicate that type I fibers are most susceptible to the effects of obesity, and that these fiber‐type changes can be sex specific.
Fiber polymorphism in skeletal muscles of the American lobster, Homarus americanus: continuum between slow-twitch (S1) and slow-tonic (S2) fibers
- S. Medler, Travis R Lilley, D. Mykles
- BiologyJournal of Experimental Biology
- 15 July 2004
The findings illustrate that muscle fibers in general may possess a phenotype that is intermediate between the extremes of `pure' fiber types, not only at the MHC level but also in terms of whole myofibrillar assemblages.
Muscular Alteration of Gill Geometry in vitro: Implications for Bivalve Pumping Processes
- S. Medler, H. Silverman
- Environmental ScienceThe Biological Bulletin
- 1 February 2001
Data support the idea that alteration of smooth muscle tone in the gill provides a mechanism for controlling water-pumping activities.
Eyestalk Ablation Has Little Effect on Actin and Myosin Heavy Chain Gene Expression in Adult Lobster Skeletal Muscles
- S. Medler, Kitty Brown, E. S. Chang, D. Mykles
- BiologyThe Biological Bulletin
- 1 April 2005
Low levels of polyubiquitin mRNA were significantly elevated in claw muscles from eyestalk-ablated animals with elevated circulating ecdysteroids, and patterns of MHC and actin gene expression are significantly different among slow and fast claw muscles, consistent with other recent data demonstrating co-expression of myosin isoforms in lobster muscles.
Mixing it up: the biological significance of hybrid skeletal muscle fibers
- S. Medler
- BiologyJournal of Experimental Biology
- 29 November 2019
This Review summarizes current knowledge on the relative abundance of hybrid fibers in a variety of muscles from different species and examines the possible role of differential activities of nuclei in different myonuclear domains in establishing fiber-type asymmetries.
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