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Digestion of human milk fat in healthy infants.
TLDR
This review focuses on digestion of the human milk fat globule and summarizes the current understanding of the mechanisms underlying this process in infants, and argues that the formation of the soap complex does not contribute to lipid bioavailability. Expand
Anemia in infancy is associated with alterations in systemic metabolism and microbial structure and function in a sex-specific manner: an observational study.
TLDR
Sexually dimorphic differences associated with anemia and IDA are suggestive of greater mitochondrial dysfunction and oxidative stress in male infants compared with female infants, and alterations in microbial structure and function may further contribute. Expand
Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment.
TLDR
Analytical investigations using gas chromatography/mass spectrometry and the clinical presentation of the patients are consistent with the notion that the fumaric aciduria is caused by an inherited defect which leads to a net secretion of f Kumaric acid by the renal tubules. Expand
Excretion of Dicarboxylic and ω-1 Hydroxy Fatty Acids by Low Birth Weight Infants Fed with Medium-Chain Triglycerides
TLDR
There were significant differences in the urinary excretions of octanoate, sebacate, suberate, adipate, 7-hydroxyoctanoates, and 5-Hydroxyhexanoate; these substances appearing in much greater quantities in the urine during the period in which medium-chain triglycerides were predominant in the formula. Expand
Specific binding of [3H]oxytocin in the female rat brain.
TLDR
The distribution in limbic tissue of oxytocin-degrading activity and of individual enzymes capable of degrading Oxytocin has been examined and an interplay of enzymes concentrated in different cell types is proposed. Expand
Optimization of a Method for the Simultaneous Extraction of Polar and Non-Polar Oxylipin Metabolites, DNA, RNA, Small RNA, and Protein from a Single Small Tissue Sample
TLDR
A modified Folch extraction method is combined with DNA, RNA, small RNA, and protein extraction using two commercial kits, which allowed us to extract polar metabolites and non-polar oxylipin metabolites, DNA, RNAs, and proteins simultaneously from a small tissue sample. Expand
Metabolomic changes in severe acute malnutrition suggest hepatic oxidative stress: a secondary analysis
TLDR
Changes in the hepatic metabolome suggest that SAM is associated with elevated hepatic oxidative stress, increased gluconeogenesis, and alterations in 1-carbon metabolism. Expand
Effectiveness of vitamin D supplementation in Swedish children may be negatively impacted by BMI and serum fructose.
TLDR
The results suggest that although the metabolic changes associated with improved vitamin D status are small, the effectiveness of dietary supplementation may be influenced by serum fructose concentrations. Expand
Early-Life Iron Supplementation Alters Whole Body Iron Homeostasis, Serum Metabolites, and Social Novelty Discrimination in Pre-Weanling Pigs
TLDR
The correct amount of iron supplementation is still needed during infancy to prevent the potential risk of iron deficiency and iron deficiency anemia. Expand
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