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Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
Neurodevelopmental disorders, including autism spectrum disorder (ASD), are defined by core behavioral impairments; however, subsets of individuals display a spectrum of gastrointestinal (GI)Expand
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A microbial symbiosis factor prevents intestinal inflammatory disease
Humans are colonized by multitudes of commensal organisms representing members of five of the six kingdoms of life; however, our gastrointestinal tract provides residence to both beneficial andExpand
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The gut microbiota shapes intestinal immune responses during health and disease
Immunological dysregulation is the cause of many non-infectious human diseases such as autoimmunity, allergy and cancer. The gastrointestinal tract is the primary site of interaction between the hostExpand
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Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
To maintain intestinal health, the immune system must faithfully respond to antigens from pathogenic microbes while limiting reactions to self-molecules. The gastrointestinal tract represents aExpand
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An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
The mammalian gastrointestinal tract harbors a complex ecosystem consisting of countless bacteria in homeostasis with the host immune system. Shaped by evolution, this partnership has potential forExpand
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Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
The intestinal microbiota influence neurodevelopment, modulate behavior, and contribute to neurological disorders. However, a functional link between gut bacteria and neurodegenerative diseasesExpand
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Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
Although the effects of commensal bacteria on intestinal immune development seem to be profound, it remains speculative whether the gut microbiota influences extraintestinal biological functions.Expand
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Gut biogeography of the bacterial microbiota
Animals assemble and maintain a diverse but host-specific gut microbial community. In addition to characteristic microbial compositions along the longitudinal axis of the intestines, discreteExpand
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Animals in a bacterial world, a new imperative for the life sciences
In the last two decades, the widespread application of genetic and genomic approaches has revealed a bacterial world astonishing in its ubiquity and diversity. This review examines how a growingExpand
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Passage of Heme-Iron Across the Envelope of Staphylococcus aureus
The cell wall envelope of Gram-positive pathogens functions as a scaffold for the attachment of virulence factors and as a sieve that prevents diffusion of molecules. Here the isdgenesExpand
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