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Identification of a high-virulence clone of type III Streptococcus agalactiae (group B Streptococcus) causing invasive neonatal disease.
Chromosomal genotypes of 128 isolates of six serotypes of Streptococcus agalactiae recovered predominantly from human infants in the United States were characterized by an analysis of electrophoretically demonstrable allelic profiles at 11 metabolic enzyme loci. Expand
Measurement of intracellular iodophilic polysaccharide in two cariogenic strains of Streptococcus mutans by cytochemical and chemical methods.
Quantitative cytological and chemical methods have been developed to study the intracellular iodophilic polysaccharide (IPS) content of two strains of Streptococcus mutans. The cytological methodExpand
Role of energy metabolism in conversion of nonmucoid Pseudomonas aeruginosa to the mucoid phenotype.
A significant role for the energy state of the cell in conversion toMucoid and in selection for the mucoid phenotype is demonstrated. Expand
Identification of a high-virulence clone of serotype III Streptococcus agalactiae by growth characteristics at 40 degrees C.
A simple procedure involving growth at 40 degrees C distinguished all isolates classified in this high-virulence clone from other serotype III isolates, which are more frequently associated with asymptomatically colonized infants, as well as the other serotypes of group B streptococci. Expand
Role of cellular lipoteichoic acids in mediating adherence of serotype III strains of group B streptococci to human embryonic, fetal, and adult epithelial cells.
Results indicate that possible receptor sites for LTA present on cells in prenatal stages of development may differ from those of adult cells, which may result in increased susceptibility of newborn infants to group B streptococcal disease. Expand
Growth and amino acid requirements of various strains of group B streptococci.
The group B streptococci, with minor exceptions, were very homogeneous in their amino acid requirements under both aerobic and anaerobic growth conditions. Expand
Lectin-biotin assay for slime present inin situ biofilm produced byStaphylococcus epidermidis using transmission electron microscopy (TEM)
Results indicate the usefulness of WGA lectin as a specific marker for detection of the presence and distribution of slime matrix material in S. epidermidis biofilm. Expand
Environmental conditions which influence mucoid conversion Pseudomonas aeruginosa PAO1.
Growth and conversion to the mucoid phenotype by nonmucoid Pseudomonas aeruginosa PAO1 was studied in a chemostat system under conditions designed to reflect those likely to be present during chronicExpand
In vivo regulation of virulence in Pseudomonas aeruginosa associated with genetic rearrangement.
Conversion to the mucoid phenotype was associated with rearrangement of chromosomal DNA upstream of the exotoxin A gene and analysis of DNA from revertant organisms revealed hybridization patterns identical to the original PAO organism. Expand
Comparative analysis of the localization of lipoteichoic acid in Streptococcus agalactiae and Streptococcus pyogenes.
Results suggest that under normal growth conditions, the hydrophobic region (glycolipid) of LTA remains associated with the cytoplasmic membrane of GBS and unavailable forHydrophobic interactions at the cell surface with epithelial cells, in contrast, release of L TA into the environment by the GAS allows the fatty acid moieties to interact with hydrophilic domains on the surface of epithelial Cells. Expand