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Tensional homeostasis and the malignant phenotype.
Regional, directional, and age-dependent properties of the brain undergoing large deformation.
Mixed porcine gray/white matter samples were obtained from animals at "infant" and "toddler" stages of neurological development, and shear properties compared to those in the adult, demonstrating that brain tissue is inhomogeneous.
Are in vivo and in situ brain tissues mechanically similar?
A proposed tolerance criterion for diffuse axonal injury in man.
The shaken baby syndrome. A clinical, pathological, and biomechanical study.
- A. Duhaime, T. Gennarelli, L. Thibault, D. Bruce, S. Margulies, R. Wiser
- MedicineJournal of neurosurgery
- 1 March 1987
It was concluded that severe head injuries commonly diagnosed as shaking injuries require impact to occur and that shaking alone in an otherwise normal baby is unlikely to cause the shaken baby syndrome.
Infant skull and suture properties: measurements and implications for mechanisms of pediatric brain injury.
Computational simulations demonstrate that the comparatively compliant skull and membranous suture properties of the infant brain case are associated with large cranial shape changes, and a more diffuse pattern of brain distortion than when the skull takes on adult properties.
Age-dependent material properties of the porcine cerebrum: effect on pediatric inertial head injury criteria.
FINITE ELEMENT MODELING APPROACHES FOR PREDICTING INJURY IN AN EXPERIMENTAL MODEL OF SEVERE DIFFUSE AXONAL INJURY
This study clearly demonstrated that the modeling approach which represented the relative motion between the skull and cerebral cortex as a frictional interface best predicted the resulting injury pattern in a 5th axial plane animal experiment.
Material characterization of the brainstem from oscillatory shear tests.