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Androgens in pregnancy: roles in parturition

The increase in androgen levels throughout gestation is likely to be important for establishment and maintenance of pregnancy and initiation of parturition and further investigation of the underlying mechanisms of androgen action on cervical remodelling and myometrial contractility is needed.
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Perimenopausal management of ovarian endometriosis and associated cancer risk: When is medical or surgical treatment indicated?

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Expression of Matrix Metalloproteinases in the Mouse Uterus and Human Myometrium During Pregnancy, Labor, and Preterm Labor

The data implicate M MP-3, TIMP-1, and MMP-10 in the uterine ECM remodeling during physiological and pathological parturition.
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Does Endometriosis Influence the Embryo Quality and/or Development? Insights from a Large Retrospective Matched Cohort Study

No difference was found between women with and without endometriosis regarding the number of cleavage stage embryos obtained as well as the percentage of good/fair quality embryos, and a reduction in ongoing pregnancy rate was observed in patients affected.
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Inside the Endometrial Cell Signaling Subway: Mind the Gap(s)

A comprehensive and critical assessment of the literature was performed to provide the tools for the authorship of this narrative review summarizing the pivotal components and signaling cascades operating during seven endometrial cell fate “routes”: proliferation, decidualization, implantation, migration, breakdown, regeneration and angiogenesis.
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Human Cathelicidin Production by the Cervix

Inducible expression of hCAP18/LL-37 in the female lower reproductive tract in vivo is demonstrated and the capacity for this peptide to modulate host defence to infection in this system is suggested.
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Abnormal sperm concentration and motility as well as advanced paternal age compromise early embryonic development but not pregnancy outcomes: a retrospective study of 1266 ICSI cycles

Male factor infertility and advanced paternal age may compromise fertilization and blastulation rates but not top quality blastocyst formation rate or the establishment of pregnancy in ICSI cycles.
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Ultrasound-guided intrauterine injection of lipopolysaccharide as a novel model of preterm birth in the mouse.

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Androgen-Induced Relaxation of Uterine Myocytes Is Mediated by Blockade of Both Ca(2+) Flux and MLC Phosphorylation.

Lipid-soluble androgens could be developed as tocolytic agents for the treatment of preterm labor by examining the potential of androgens to relax the myometrium and the mechanism of their action.
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The preterm cervix reveals a transcriptomic signature in the presence of premature prelabor rupture of membranes

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