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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily.
- M. Bootcov, A. Bauskin, +13 authors S. Breit
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 14 October 1997
Macrophages play a key role in both normal and pathological processes involving immune and inflammatory responses, to a large extent through their capacity to secrete a wide range of biologically… Expand
Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells
A recombinant CHO cell line in which the expresison of human follicle stimulating hormone (hFSH) was under the control of the β actin promoter was maintained in steady state perfusion cultures on a… Expand
Hypothermic Storage and Cryopreservation of Hepatocytes: The Protective Effect of Alginate Gel against Cell Damages
Hepatocyte-based therapy has been proposed as an alternative to organ transplantation in the treatment of liver disorders. In the clinical context, a major issue is the constant supply of quality… Expand
Follow‐up by one‐ and two‐dimensional NMR of plasma from pigs with ischemia‐induced acute liver failure treated with a bioartificial liver
Hepatic encephalopathy may occur following acute hepatic failure (AHF), which results in the release of toxic compounds from the injured liver. These compounds, which induce cerebral edema, are not… Expand
The effectiveness of different rat IgG subclasses as IgE‐blocking antibodies in the rat basophil leukaemia cell model
- J. R. Philips, W. Brouwer, M. Edwards, S. Mahler, J. Ruhno, A. Collins
- Biology, Medicine
- Immunology and cell biology
- 1 April 1999
The degranulation of mast cells in an allergic response is initiated by the aggregation of high‐ affinity IgE receptors (FcεRI) by IgE and antigen. Recently it has been shown that such degranulation… Expand
Mast cell tumour in a young boxer dog
- S. Mahler
- Veterinary Record
- 17 August 2012
A FOUR-WEEK-OLD male boxer dog was seen with a firm, not painful, cutaneous mass in the left ventral and cranial abdomen region (Fig 1), which the breeder had first noticed 10 days before. The… Expand
Secondary Ossification Centre at the Acetabular Dorsal Rim in a Dog: Radiographic and MRI Observations
The mineralisation of a secondary ossification centre, in the formation of the canine acetabulum, is discussed. Its role in the subluxation of the femoral head in hip dysplasia is put up for… Expand
Reduced encephalopathy in pigs with ischemia-induced acute hepatic failure treated with a bioartificial liver containing alginate-entrapped hepatocytes.
OBJECTIVE To analyze the effects of an extracorporeal bioartificial liver containing alginate bead-entrapped hepatocytes on pigs with ischemia-induced acute hepatic failure. DESIGN Prospective… Expand
Improvement of the neurological status of pigs with acute liver failure by hepatocytes immobilized in alginate gel beads inoculated in an extracorporeal bioartificial liver.