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- Publications
- Influence
Venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukaemia: a phase 1b study.
- J. Seymour, S. Ma, +20 authors A. Roberts
- Medicine
- The Lancet. Oncology
- 1 February 2017
BACKGROUND
Selective BCL2 inhibition with venetoclax has substantial activity in patients with relapsed or refractory chronic lymphocytic leukaemia. Combination therapy with rituximab enhanced… Expand
Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration
- S. Shaw, S. Ma, +9 authors F. Luscinskas
- Biology, Medicine
- The Journal of experimental medicine
- 20 December 2004
The leukocyte integrin lymphocyte function-associated antigen 1 (LFA-1) and its endothelial ligand intercellular adhesion molecule (ICAM)-1 play an important role in transmigration as demonstrated by… Expand
Cytoplasmic dynein-associated structures move bidirectionally in vivo.
- S. Ma, R. Chisholm
- Biology, Medicine
- Journal of cell science
- 1 April 2002
Intracellular organelle transport is driven by motors that act upon microtubules or microfilaments. The microtubulebased motors, cytoplasmic dynein and kinesin, are believed to be responsible for… Expand
Dynein Intermediate Chain Mediated Dynein–Dynactin Interaction Is Required for Interphase Microtubule Organization and Centrosome Replication and Separation inDictyostelium
- S. Ma, L. Triviños-Lagos, R. Gräf, R. Chisholm
- Biology, Medicine
- The Journal of cell biology
- 13 December 1999
Cytoplasmic dynein intermediate chain (IC) mediates dynein–dynactin interaction in vitro (Karki, S., and E.L. Holzbaur. 1995. J. Biol. Chem. 270:28806–28811; Vaughan, K.T., and R.B. Vallee. 1995. J.… Expand
Nuclear overexpression of lymphoid-enhancer-binding factor 1 identifies chronic lymphocytic leukemia/small lymphocytic lymphoma in small B-cell lymphomas
- Bevan Tandon, L. Peterson, +4 authors Y. Chen
- Biology, Medicine
- Modern Pathology
- 1 November 2011
Lymphoid-enhancer-binding factor 1 (LEF1), coupling with β-catenin, functions as a key nuclear mediator of WNT/β-catenin signaling, which regulates cell proliferation and survival. LEF1 has an… Expand
Regulation of Leukocyte Transmigration: Cell Surface Interactions and Signaling Events 1
- Y. Liu, S. Shaw, S. Ma, L. Yang, F. Luscinskas, C. Parkos
- Biology, Medicine
- The Journal of Immunology
- 1 January 2004
A fundamental event in the inflammatory response is recruitment of blood leukocytes to a site of injury or infection, often resulting in tissue dysfunction and damage. The steps in this recruitment… Expand
Leukocyte transendothelial migration: a junctional affair.
- F. Luscinskas, S. Ma, A. Nusrat, C. Parkos, S. Shaw
- Biology, Medicine
- Seminars in immunology
- 1 April 2002
A critical function of the inflammatory response is delivery of leukocytes to a site of injury, immune reaction or infection. Considerable information is available concerning the molecular mechanisms… Expand
Nuclear protein dysregulation in lymphoplasmacytic lymphoma/waldenstrom macroglobulinemia.
- Mark J. Roberts, A. Chadburn, S. Ma, E. Hyjek, L. Peterson
- Medicine
- American journal of clinical pathology
- 1 February 2013
Waldenström macroglobulinemia (WM) is characterized by monoclonal gammopathy, usually IgM, in association with lymphoplasmacytic lymphoma (LPL). Little is known of the expression of nuclear proteins… Expand
Phase II study of alemtuzumab–rituximab therapy in previously untreated patients with chronic lymphocytic leukemia: short- and long-term outcomes
- O. Frankfurt, S. Ma, +9 authors S. Rosen
- Medicine
- Leukemia & lymphoma
- 1 February 2015
Abstract We investigated the safety, efficacy, and long-term outcomes of alemtuzumab and rituximab (AR) combination therapy in previously untreated patients with CLL. Thirty patients, ages 28–80… Expand
PD‐1 is highly expressed by neoplastic B‐cells in Richter transformation
- A. Behdad, B. Griffin, +4 authors Q. Chen
- Medicine
- British journal of haematology
- 1 April 2019
Hayes, J.D., Flanagan, J.U. & Jowsey, I.R. (2005) Glutathione transferases. Annual Review of Pharmacology and Toxicology, 45, 51–88. Korkolopoulou, P., Thymara, I., Kavantzas, N., Vassilakopoulos,… Expand