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Role of dynamin in the formation of transport vesicles from the trans-Golgi network.
Data suggest that dynamin participates in the formation of distinct transport vesicles from the trans-Golgi network, and that budding efficiency was restored upon readdition of purified dynamin.
Characterization of the Golgi complex cleared of proteins in transit and examination of calcium uptake activities.
- R. Taylor, S. M. Jones, R. Dahl, M. Nordeen, K. Howell
- BiologyMolecular Biology of the Cell
- 1 October 1997
To characterize endogenous molecules and activities of the Golgi complex, proteins in transit were > 99% cleared from rat hepatocytes by using cycloheximide (CHX) treatment and electron microscopy and morphometric analysis showed that > 90% of the elements could be positively identified as Golgi stacks or cisternae.
A cytosolic complex of p62 and rab6 associates with TGN38/41 and is involved in budding of exocytic vesicles from the trans-Golgi network
An essential role for interaction of the cytosolic p62/rab6 complex with TGN38/41 in budding of exocytic vesicles from the TGN is supported and preliminary evidence indicates that phosphorylation of the p62 molecule regulates the dissociation from TGN 38/41.
Neuropharmacology of phencyclidine: basic mechanisms and therapeutic potential.
Overexpression of a potassium channel gene perturbs neural differentiation
It is suggested that, by prematurely reducing the duration of the impulse, early overexpression of potassium channel activity suppresses normal developmental cues.
The Ebola virus ribonucleoprotein complex: a novel VP30-L interaction identified.
GOLAC: an endogenous anion channel of the Golgi complex.
Intermediate Filament Networks: Organization and Possible Functions of a Diverse Group of Cytoskeletal Elements
- R. Goldman, A. Goldman, K. Green, J. Jones, S. M. Jones, H. Yang
- BiologyJournal of Cell Science
- 1 February 1986
The results support the idea that IF and their associated proteins may comprise the cell type specific molecular infrastructure that is involved in transmitting and distributing information amongst the major cellular domains; the cell surface/extracellular matrix, the cytoplasm and the nuclear surface/nuclear matrix.
Vagal and gastric connections to the central nervous system determined by the transport of horseradish peroxidase
Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
- J. Ferkany, D. Kyle, S. Borosky
- Biology, ChemistryThe Journal of pharmacology and experimental…
- 1 July 1989
The results of the current study indicate that NPC 12626 is a novel, systemically active and competitive NMDA receptor antagonist.