• Publications
  • Influence
Host-induced epidemic spread of the cholera bacterium
The factors that enhance the transmission of pathogens during epidemic spread are ill defined. Water-borne spread of the diarrhoeal disease cholera occurs rapidly in nature, whereas infection ofExpand
  • 473
  • 13
  • PDF
Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae.
The role of chemotaxis in the virulence of gastrointestinal pathogens is ill defined. Counterintuitively, nonchemotactic mutants of the polarly flagellated pathogen Vibrio cholerae greatlyExpand
  • 168
  • 12
  • PDF
Going against the grain: chemotaxis and infection in Vibrio cholerae
Chemotaxis is the process by which motile cells move in a biased manner both towards favourable and away from unfavourable environments. The requirement of this process for infection has beenExpand
  • 322
  • 10
Selection for in vivo regulators of bacterial virulence
We devised a noninvasive genetic selection strategy to identify positive regulators of bacterial virulence genes during actual infection of an intact animal host. This strategy combines randomExpand
  • 194
  • 10
  • PDF
A Teacher's Guide to Classroom Assessment: Understanding and Using Assessment to Improve Student Learning
Figures, Tables, and Exhibits. Foreword (Ken O'Connor). Preface. Acknowledgments. About the Authors. Introduction: Assessment for Classroom Learning. 1. Understanding the Varieties of Assessment.Expand
  • 41
  • 5
  • PDF
A novel regulatory protein involved in motility of Vibrio cholerae.
The facultative pathogen Vibrio cholerae is the causative agent of the human intestinal disease cholera. Both motility and chemotaxis of V. cholerae have been shown to contribute to the virulence andExpand
  • 34
  • 4
  • PDF
Self‐compartmentalized bacterial proteases and pathogenesis
Protein degradation is required for homeostasis of all living organisms. Self‐compartmentalized ATP‐dependent proteases are required for virulence of several pathogenic bacteria. Among the proteasesExpand
  • 113
  • 3
Cholera stool bacteria repress chemotaxis to increase infectivity
Factors that enhance the transmission of pathogens are poorly understood. We show that Vibrio cholerae shed in human ‘rice‐water’ stools have a 10‐fold lower oral infectious dose in an animal modelExpand
  • 74
  • 3
Designing a Technology-Based Science Lesson: Student Teachers Grapple with an Authentic Problem of Practice
TLDR
This project used techniques from problem-based learning to aid students in developing a technology-based science lesson. Expand
  • 10
  • 2
  • PDF
Group embedded figures test and academic achievement in engineering education
This study was conducted to investigate cognitive style patterns among students in a lower divisionengineering course and differences in the academic performance of those students relatedExpand
  • 15
  • 1