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ISG'ylation increases stability of numerous proteins including Stat1, which prevents premature termination of immune response in LPS-stimulated microglia
The results suggest that increased ISG'ylation in LPS‐stimulated microglia supports stability of proteins, including Stat1, which prevents termination of immune responses during inflammation.
Regulation of ULK1 in autophagy
Pim1 (Proto-oncogene serine/threonine-protein kinase pim-1) phosphorylated ULK1 in�vitro at S147 and S224, and preliminary data suggesting that Pim1 promotes autophagy in HeLa cells is presented.