Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Structure and mechanism of carbonic anhydrase.
- S. Lindskog
- Chemistry, Medicine
- Pharmacology & therapeutics
- 1997
Carbonic anhydrase (CA; carbonate hydro-lyase, EC 4.2.1.1) is a zinc-containing enzyme that catalyzes the reversible hydration of carbon dioxide: CO2+ H2O<-->HCO3(-)+H+. The enzyme is the target for… Expand
The catalytic mechanism of carbonic anhydrase: implications of a rate-limiting protolysis of water
- D. Silverman, S. Lindskog
- Chemistry
- 1988
Purification and properties of bovine erythrocyte carbonic anhydrase.
- S. Lindskog
- Chemistry, Medicine
- Biochimica et biophysica acta
- 8 April 1960
Abstract 1. 1. A new method for the purification of bovine erythrocyte carbonic anhydrase is described. The procedure invo;ves chromatography on DEAE cellulose ion exchanger and zone electrophoresis… Expand
Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant.
- C. Tu, D. Silverman, C. Forsman, B. Jonsson, S. Lindskog
- Chemistry, Medicine
- Biochemistry
- 19 September 1989
To test the hypothesis that histidine 64 in the active site of human carbonic anhydrase II functions as a proton-transfer group in the catalysis of CO2 hydration, we have studied a site-specific… Expand
The complete sequence, expression in Escherichia coli, purification and some properties of carbonic anhydrase from Neisseria gonorrhoeae.
- L. Chirica, B. Elleby, B. Jonsson, S. Lindskog
- Biology, Medicine
- European journal of biochemistry
- 1 March 1997
The complete nucleotide sequence of the carbonic anhydrase gene from Neisseria gonorrhoeae has been determined. The gene encodes a 252-residue polypeptide with a molecular mass of 28085 Da. The gene… Expand
Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
- S. Huang, Y. Xue, E. Sauer-Eriksson, L. Chirica, S. Lindskog, B. Jonsson
- Chemistry, Medicine
- Journal of molecular biology
- 16 October 1998
The crystal structure of carbonic anhydrase from Neisseria gonorrhoeae has been solved to a resolution of 1.78 A by molecular replacement using human carbonic anhydrase II as a template. After… Expand
The catalytic mechanism of mammalian carbonic anhydrases.
- S. Lindskog, D. Silverman
- Chemistry, Medicine
- EXS
- 2000
The physiological reaction catalyzed by carbonic anhydrase (CA) involves only six atoms at the substrate level: CO2 + H2O ↔ HCO 3 – + H+ Despite this simplicity, some aspects of the catalytic… Expand
Cloning, expression and some properties of α-carbonic anhydrase from Helicobacter pylori
- L. C. Chirica, B. Elleby, S. Lindskog
- Chemistry
- 12 January 2001
The -carbonic anhydrase gene from Helicobacter pylori strain 26695 has been cloned and sequenced. The full-length protein appears to be toxic to Escherichia coli, so we prepared a modified form of ...
METAL-BINDING PROPERTIES OF HUMAN ERYTHROCYTE CARBONIC ANHYDRASES.
- S. Lindskog, P. Nyman
- Chemistry, Medicine
- Biochimica et biophysica acta
- 1 June 1964
Abstract 1. 1. The zinc ion can be reversibly removed from both high specific activity (C) and low specific activity (B) carbonic anhydrases (carbonate hydro-lyase, EC 4.2.1.1) of human red blood… Expand
The catalytic mechanism of carbonic anhydrase.
- S. Lindskog, J. Coleman
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 November 1975
It is shown that an "inverse" relationship between the pH dependencies of the rates of hydration of CO(2) and dehydration of HCO(3) (-) by carbonic anhydrase (EC 4.2.1.1) is a direct consequence of… Expand