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Preliminary results of a prospective randomized trial comparing concurrent chemoradiotherapy plus adjuvant chemotherapy with radiotherapy alone in patients with locoregionally advanced nasopharyngeal
  • Yong Chen, M. Liu, +7 authors J. Ma
  • Medicine
    International journal of radiation oncology…
  • 1 August 2008
TLDR
This trial demonstrated the significant survival benefits of concurrent chemotherapy plus adjuvant chemotherapy in patients with locoregionally advanced NPC in endemic regions of China.
Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled
TLDR
Addition of TPF induction chemotherapy to concurrent chemoradiotherapy significantly improved failure-free survival in locoregionally advanced nasopharyngeal carcinoma with acceptable toxicity.
Concurrent chemoradiotherapy plus adjuvant chemotherapy versus concurrent chemoradiotherapy alone in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 3 multicentre randomised
TLDR
Adjuvant cisplatin and fluorouracil chemotherapy did not significantly improve failure-free survival after concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma and such regimens should not be used outside well-designed clinical trials.
The volume to be irradiated during selective neck irradiation in nasopharyngeal carcinoma
TLDR
The spread pattern of lymph node metastases in patients with nasopharyngeal carcinoma (NPC) metastases is analyzed using magnetic resonance imaging (MRI) and the efficacy of selective neck irradiation was assessed based on the volume irradiated.
The N Staging System in Nasopharyngeal Carcinoma with Radiation Therapy Oncology Group Guidelines for Lymph Node Levels Based on Magnetic Resonance Imaging
TLDR
The proposed N staging system of NPC using RTOG guidelines based on MRI is highly predictive and may provide a more objective method for staging NPCs.
Extension of local disease in nasopharyngeal carcinoma detected by magnetic resonance imaging: improvement of clinical target volume delineation.
  • S. Liang, Ying Sun, +9 authors J. Ma
  • Medicine
    International journal of radiation oncology…
  • 1 November 2009
TLDR
By MRI the local extension patterns in patients presenting with nasopharyngeal carcinoma are defined to improve clinical target volume delineation and selective radiotherapy of the local disease in NPC may be feasible.
Development and External Validation of Nomograms for Predicting Survival in Nasopharyngeal Carcinoma Patients after Definitive Radiotherapy
TLDR
Nomograms incorporating plasma EBV DNA for predicting DMFS and OS of nasopharyngeal carcinoma patients after definitive radiotherapy allowed significant distinction between Kaplan-Meier curves for survival outcomes.
Prognostic impact of magnetic resonance imaging‐detected cranial nerve involvement in nasopharyngeal carcinoma
The purpose of this study was to evaluate the prognostic value of magnetic resonance imaging (MRI)‐detected cranial nerve (CN) involvement in nasopharyngeal carcinoma (NPC).
Progress report of a randomized trial comparing long‐term survival and late toxicity of concurrent chemoradiotherapy with adjuvant chemotherapy versus radiotherapy alone in patients with stage III to
The objective of this study was to evaluate the long‐term survival and late toxicities of concurrent‐adjuvant chemotherapy in patients with stage III through IVB nasopharyngeal carcinoma (NPC) from
Concurrent chemoradiotherapy with/without induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: Long‐term results of phase 3 randomized controlled trial
TLDR
Long‐term follow‐up confirmed that TPF IC plus CCRT significantly improved survival in locoregionally advanced NPC with no marked increase in late toxicities and could be an option of treatment for these patients.
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