• Publications
  • Influence
Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization
Significance The two pepper genomes together with 20 resequencing accessions, including 3 accessions that are classified as semiwild/wild, provide a better understanding of the evolution,Expand
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Calibur: a tool for clustering large numbers of protein decoys
  • S. Li, Y. Ng
  • Computer Science, Medicine
  • BMC Bioinformatics
  • 13 January 2010
TLDR
Calibur is a software tool for clustering very large numbers of decoys in ab initio protein structure prediction. Expand
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Fragment‐HMM: A new approach to protein structure prediction
TLDR
We designed a simple position‐specific hidden Markov model to predict protein structure. Expand
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Coding mutations in NUS1 contribute to Parkinson’s disease
  • J. Guo, L. Zhang, +37 authors B. Tang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 22 October 2018
Significance Parkinson’s disease (PD) is the second most common neurodegenerative disorder in the world. Several common and rare genetic risk variants associated with PD pathogenesis have beenExpand
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Pedigree Reconstruction Using Identity by Descent
TLDR
This article introduces two multi-generational pedigree reconstruction methods: one for inbreeding relationships and one for outbreeding relationships that out-perform the state-of-the-art. Expand
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Finding Largest Well-Predicted Subset of Protein Structure Models
TLDR
How to evaluate the quality of models is a basic problem for the field of protein structure prediction. We present a (1 + i¾?)ddistance approximation algorithm that runs in time O(n3logn/i¾?5) for general protein structures. Expand
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Error Tolerant NMR Backbone Resonance Assignment and Automated Structure Generation
TLDR
We have designed an integer linear programming (ILP) based assignment system (IPASS) that has enabled fully automatic protein structure determination for four test proteins. Expand
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Spectral probabilities of top-down tandem mass spectra
TLDR
We study an extended generating function method for accurately computing the statistical significance of protein-spectrum matches with post-translational modifications in bottom-up mass spectrometry. Expand
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Indexing DNA Sequences Using q-Grams
TLDR
We propose a method for indexing the DNA sequences efficiently based on q-grams to facilitate similarity search in a DNA database and sidestep the need for linear scan of the entire database. Expand
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Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities
The gut microbiota (GM) is related to obesity and other metabolic diseases. To detect GM markers for obesity in patients with different metabolic abnormalities and investigate their relationshipsExpand
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