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Whole-genome analyses resolve early branches in the tree of life of modern birds
TLDR
A genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves recovered a highly resolved tree that confirms previously controversial sister or close relationships and identifies the first divergence in Neoaves, two groups the authors named Passerea and Columbea. Expand
Comparative genomics reveals insights into avian genome evolution and adaptation
TLDR
This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits. Expand
Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin
TLDR
It is shown that the astrocytic dopamine D2 receptor (DRD2) modulates innate immunity through αB-crystallin (CRYAB), which is known to suppress neuroinflammation in the central nervous system through a CRYAB-dependent mechanism. Expand
Compartmentalization of Simian Immunodeficiency Virus Replication within Secondary Lymphoid Tissues of Rhesus Macaques Is Linked to Disease Stage and Inversely Related to Localization of
TLDR
The hypothesis that B cell follicles are immune privileged sites could lead to improved viral control and possibly a functional cure for HIV infection is bolstered and strategies to augment CTL in B cell hair follicles could be suggested. Expand
Potential association of DRD2 and DAT1 genetic variation with heroin dependence
TLDR
The results showed that DRD2 TaqI A1 allele carriers were prone to heroin abuse in models of dominance or co-dominance and there was no gene interaction between the two genetic loci. Expand
Novel mutations in ubiquitin-specific protease 26 gene might cause spermatogenesis impairment and male infertility.
TLDR
The USP26 gene might be of importance in male reproduction, and might negatively affect testicular function, as well as being associated with male infertility, and some substitutions predict some changes. Expand
A functional polymorphism in IL-1A gene is associated with a reduced risk of gastric cancer
TLDR
It is found that the ins/ins (ttca/ttca) genotype of thers3783553 polymorphism was associated with a significantly decreased risk of GC, suggesting that the rs37835 53 polymorphism may be a protective factor for the development of GC. Expand
Association Study Identifying a New Susceptibility Gene (AUTS2) for Schizophrenia
TLDR
The results confirm previous reports which have suggested that rs6943555 might elucidate the pathogenesis of schizophrenia and play an important role in its etiology and were determined to be associated with female SCZ. Expand
The dopamine D1 but not D3 receptor plays a fundamental role in spatial working memory and BDNF expression in prefrontal cortex of mice
TLDR
It is found that trial-dependent, matching-to-sample, learning of the platform location, an index of short-term spatial working memory in mice, was significantly impaired in D1 receptor knockout mice compared to wild-type mice, and regular performance of D3 receptor mutants was observed in the similar working memory task. Expand
Preliminary DNA Identification for the Tsunami Victims in Thailand
TLDR
It is concluded that the Thai tsunami victims are a combined group of several populations, including foreign tourists and local residents as well as both mitochondrial and nuclear markers. Expand
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