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- Publications
- Influence
Effect of DA‐8031, a novel oral compound for premature ejaculation, on male rat sexual behavior
- K. K. Kang, J. Sung, S. H. Kim, S. Lee
- Medicine
- International journal of urology : official…
- 1 March 2014
DA‐8031 is a potent and selective serotonin transporter inhibitor developed for the treatment of premature ejaculation. The aim of the present study was to investigate the effects of DA‐8031 on male… Expand
Ejaculatory responses are inhibited by a new chemical entity, DA-8031, in preclinical rodent models of ejaculation.
OBJECTIVE
To investigate the efficacy of DA-8031, a novel compound for the treatment of premature ejaculation (PE), we performed in vivo pharmacological studies using 2 preclinical animal models,… Expand
Effect of the potent CYP2D6 inhibitor sarpogrelate on the pharmacokinetics and pharmacodynamics of metoprolol in healthy male Korean volunteers
- Doo-Yeoun Cho, S. Bae, +6 authors S. Bae
- Medicine
- Xenobiotica; the fate of foreign compounds in…
- 26 February 2015
Abstract 1. Recently, we demonstrated that sarpogrelate is a potent and selective CYP2D6 inhibitor in vitro. Here, we evaluated the effect of sarpogrelate on the pharmacokinetics and pharmacodynamics… Expand
Determination of Defined Daily Dose of Medicines using Nominal Group Technique and Analysis of Antibiotics Use in National Insurance Claim Data: Focused on Antibiotics without DDD of WHO
- Dong-Sook Kim, Namsoon Kim, S. Lee
- Medicine
- 30 June 2007
Objectives : It is necessary to monitor consumption of drugs in order to enhance promote appropriate use of drugs. Defined Daily Dose(DDD) of World Health Organization(WHO) has been used for… Expand
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Comparison of Hyperkalemic Risk in Hospitalized Patients Treated with Different Angiotensin Receptor Blockers
- I. Park, S. Sheen, +6 authors R. Park
- Medicine
- American Journal of Cardiovascular Drugs
- 12 December 2012
Background and AimClinical use of angiotensin II type 1 receptor antagonists (angiotensin receptor blockers [ARBs]) is associated with hyperkalemia as an adverse drug reaction. Although it has… Expand
Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea
Introduction Aspirin is widely used to prevent cardiovascular diseases (CVDs). However, the balance of its benefits and risks in the primary prevention of CVDs and cancer is unclear, especially in… Expand
Impact of Statin Use on Dementia Incidence in Elderly Men and Women with Ischemic Heart Disease
This study aimed to determine the association between statins and the prevention of dementia according to sex differences in elderly patients with ischemic heart disease (IHD). We performed a… Expand
Comprehensive Trends and Patterns of Antihypertensive Prescriptions Using a Nationwide Claims Database in Korea
- M. Jung, Eunjung Choo, S. Lee
- Medicine
- Clinical epidemiology
- 11 September 2020
Purpose The number of people receiving antihypertensive prescriptions in Korea has increased more than threefold from 2002 to 2016. However, previous studies regarding the current use of these… Expand
Dissolution test for liquid formulations of omeprazole enteric-coated products
- H. J. Jang, B. C. Kang, W. G. Shin, S. Lee
- Medicine
- The Annals of pharmacotherapy
- 1 January 2003
Comparison of Moxifloxacin Monotherapy versus Cephalosporin -Azithromycin Combination Therapies for the Treatment ofCommunity Acquired Pneumonia
Background and Objective Community acquired pneumonia (CAP) remains a prevalent and potentially life threatening illness. American Thoracic Society and Infectious Disease Society America recommend… Expand