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Identification of novel universal housekeeping genes by statistical analysis of microarray data.
- S. Lee, M. Jo, Jungeun Lee, S. S. Koh, Soyoun Kim
- Biology, Medicine
- Journal of biochemistry and molecular biology
- 31 March 2007
Housekeeping genes are widely used as internal controls in a variety of study types, including real time RT-PCR, microarrays, Northern analysis and RNase protection assays. However, even commonly… Expand
Development of single-stranded DNA aptamers for specific Bisphenol a detection.
The development of reagents with high affinity and specificity to small molecules is crucial for the high-throughput detection of chemical compounds, such as toxicants or pollutants. Aptamers are… Expand
High-throughput genomic and proteomic analysis using microarray technology.
BACKGROUND High-density microarrays are ideally suited for analyzing thousands of genes against a small number of samples. The next step in the discovery process is to take the resulting genes of… Expand
Chip-based detection of hepatitis C virus using RNA aptamers that specifically bind to HCV core antigen.
- S. Lee, Young Sook Kim, Minjung Jo, M. Jin, D. Lee, S. Kim
- Chemistry, Medicine
- Biochemical and biophysical research…
- 22 June 2007
The development of reagents with high affinity and specificity to the antigens of hepatitis C virus (HCV) is important for the early stage diagnosis of its infection. Aptamers are short,… Expand
Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-κB activity via direct interaction with p50
Kaurane diterpene compounds have been known to be cytotoxic against several cancer cells through inhibition of nuclear factor-κB (NF-κB) activity. Here, we showed that inflexinol, a novel kaurane… Expand
Nonradioactive, colorimetric microplate hybridization assay for detecting amplified human immunodeficiency virus DNA.
A nonradioactive, colorimetric microplate hybridization procedure was used to assay human immunodeficiency virus (HIV) DNA, amplified by the polymerase chain reaction (PCR). Under the PCR conditions… Expand
Gene regulations in HBV-related liver cirrhosis closely correlate with disease severity.
Liver cirrhosis (LC) is defined as comprising diffuse fibrosis and regenerating nodules of the liver. The biochemical and anatomical dysfunction in LC results from both reduced liver cell number and… Expand
High diagnostic accuracy of antigen microarray for sensitive detection of hepatitis C virus infection.
BACKGROUND Hepatitis C virus (HCV) can be transmitted through blood transfusion. Screening ELISA, the most widely used method for HCV diagnosis, sometimes yields false-positive and false-negative… Expand
New-generation RIBA hepatitis C strip immunoblot assays.
- A. Polito, R. Dinello, +5 authors S. Lee
- Beitrage zur Infusionstherapie = Contributions to…
Second-generation hepatitis C virus (HCV) ELISAs are currently in use in Europe and have been submitted for approval in the United States. These new assays contain additional antigens from the… Expand