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Clinically significant interactions between antiretroviral and co-prescribed drugs for HIV-infected children: profiling and comparison of two drug databases
Background Drug–drug interactions are an important therapeutic challenge among human immunodeficiency virus-infected patients. Early recognition of drug–drug interactions is important, but conflictsExpand
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Potential drug–drug interactions in HIV-infected children on antiretroviral therapy in Lagos, Nigeria
Background Multi-therapy is common in HIV-infected children, and the risk for clinically significant drug interactions (CSDIs) is high. We investigated the prevalence of CSDIs between antiretroviralExpand
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Potential of novel phytoecdysteroids isolated from Vitex doniana in the treatment depression: Involvement of monoaminergic systems
Vitex doniana Sweet (Verbanaceae) is used in traditional African medicine for the treatment of neurological disorders including depression. In our previous studies, three new phytoecdysteroids wereExpand
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Antinociceptive and anti-inflammatory effects of Olax subscorpioidea Oliv. (Olacaceae) leaf extract in rodents: possible mechanisms of antinociceptive action
Background: Olax subscorpioidea Oliv. (Olacaceae) is a medicinal plant commonly used in traditional medicine to relieve pain in inflammatory processes. Objective: In the present study, the in vivoExpand
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Descriptive features of Lassa fever in Bauchi, Northeastern Nigeria - a retrospective review
Objective: Nigeria records it largest outbreak of Lassa fever in 2018, with 416 confirmed cases by 22 nd April 2018 affecting 22 states and the Federal Capital Territory (FCT). This study determinesExpand
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Potential drug‐drug interactions in HIV‐infected children on highly active antiretroviral therapy in Lagos, Nigeria
Multiple therapies are common in HIV‐infected children on highly active antiretroviral therapy (HAART). These children are at risk for clinically significant drug interactions (CSDIs). While CSDIsExpand
Eleventh International Congress on Drug Therapy in HIV Infection
The efficiency of transmission of HIV depends on the infectiousness of the index case and the susceptibility of those exposed. Infectiousness is dictated by the concentration of HIV‐1 in relevantExpand