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Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications.
Practical Interests of Magnetic NuclearRelaxation for the Characterization of Superparamagnetic Colloid, and Use of Nanoparticles as Contrast Agents forMRI20825. Expand
Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy.
This review covers recent advances in the development of SPions together with their possibilities and limitations from fabrication to application in drug delivery and the state-of-the-art synthetic routes and surface modification of desired SPIONs for drug delivery purposes. Expand
Protein-nanoparticle interactions: opportunities and challenges.
Protein Nanoparticle Interactions: Opportunities and Challenges Morteza Mahmoudi,* Iseult Lynch, Mohammad Reza Ejtehadi, Marco P. Monopoli, Francesca Baldelli Bombelli, and Sophie Laurent NationalExpand
Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles.
In this review, the limitations and recent advances in the development of superparamagnetic iron oxide nanoparticles for hyperthermia are presented. Expand
Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents.
The presence of human serum albumin has no significant effect on the proton relaxivity of Magnevist, Dotarem, Omniscan, ProHance and Gadovist but markedly increases the Relaxivity of MultiHance because of a non-covalent interaction with the protein. Expand
Classification and basic properties of contrast agents for magnetic resonance imaging.
Classification includes composition, magnetic properties, biodistribution and imaging applications, which covers all types of MRI contrast agents including, among others, extracellular, blood pool, polymeric, particulate, responsive, oral, and organ specific. Expand
Toxicity evaluations of superparamagnetic iron oxide nanoparticles: cell "vision" versus physicochemical properties of nanoparticles.
Evaluating the toxicities of three forms of superparamagnetic iron oxide nanoparticles of various surface chemistries revealed that SPIONs-COOH altered genes associated with cell proliferative responses due to their reactive oxygen species (ROS) properties. Expand
Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges
Surface modification of SPIONs can open up the possibility of drug delivery to intracellular organelles, drug delivery across the blood–brain barrier, modifying metabolic diseases and a variety of other multimodal and/or theranostic applications. Expand
Hybrid gadolinium oxide nanoparticles: multimodal contrast agents for in vivo imaging.
This study revealed that Luminescent hybrid nanoparticles suited for dual modality imaging freely circulate in the blood vessels without undesirable accumulation in lungs and liver. Expand