• Publications
  • Influence
An Energy Budget for Signaling in the Grey Matter of the Brain
Anatomic and physiologic data are used to analyze the energy expenditure on different components of excitatory signaling in the grey matter of rodent brain. Action potentials and postsynaptic effectsExpand
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A Simple Coding Procedure Enhances a Neuron's Information Capacity
  • S. Laughlin
  • Biology, Medicine
  • Zeitschrift fur Naturforschung. Section C…
  • 1 October 1981
Abstract The contrast-response function of a class of first order intemeurons in the fly's compound eye approximates to the cumulative probability distribution of contrast levels in natural scenes.Expand
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Predictive coding: a fresh view of inhibition in the retina
Interneurons exhibiting centre-surround antagonism within their receptive fields are commonly found in peripheral visual pathways. We propose that this organization enables the visual system toExpand
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The metabolic cost of neural information
We derive experimentally based estimates of the energy used by neural mechanisms to code known quantities of information. Expand
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Energy as a constraint on the coding and processing of sensory information
  • S. Laughlin
  • Biology, Medicine
  • Current Opinion in Neurobiology
  • 1 August 2001
Neurons use significant amounts of energy to generate signals. Recent studies of retina and brain connect this energy usage to the ability to transmit information. The identification ofExpand
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Colour thresholds and receptor noise: behaviour and physiology compared
Photoreceptor noise sets an absolute limit for the accuracy of colour discrimination. We compared colour thresholds in the honeybee (Apis mellifera) with this limit. Bees were trained to discriminateExpand
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Energy limitation as a selective pressure on the evolution of sensory systems
SUMMARY Evolution of animal morphology, physiology and behaviour is shaped by the selective pressures to which they are subject. Some selective pressures act to increase the benefits accrued whilstExpand
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Adaptation of the motion-sensitive neuron H1 is generated locally and governed by contrast frequency
Recordings from the motion-sensitive giant neuron H1 of the lobula plate of the fly Lucilia cuprina, indicate that small field, possibly retinotopic, units presynaptic to H1, adapt in response toExpand
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Ion-Channel Noise Places Limits on the Miniaturization of the Brain’s Wiring
The action potential (AP) is transmitted by the concerted action of voltage-gated ion channels. Thermodynamic fluctuations in channel proteins produce probabilistic gating behavior, causing channelExpand
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Communication in Neuronal Networks
Brains perform with remarkable efficiency, are capable of prodigious computation, and are marvels of communication. Expand
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