Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms.
- S. Larsson, M. Kumlin, M. Ingelman-Sundberg, A. Wolk
- BiologyAmerican Journal of Clinical Nutrition
- 1 June 2004
Several molecular mechanisms whereby n-3 fatty acids may modify the carcinogenic process have been proposed, and influences on transcription factor activity, gene expression, and signal transduction pathways; alteration of estrogen metabolism; increased or decreased production of free radicals and reactive oxygen species; and mechanisms involving insulin sensitivity and membrane fluidity are proposed.
Diabetes mellitus and risk of colorectal cancer: a meta-analysis.
- S. Larsson, N. Orsini, A. Wolk
- MedicineJournal of the National Cancer Institute
- 16 November 2005
A meta-analysis of published data on the association between diabetes and the incidence and mortality of colorectal cancer found that diabetes was associated with an increased risk of colors, compared with no diabetes, and these results were consistent between case-control and cohort studies and between studies conducted in the United States and in Europe.
Meat consumption and risk of colorectal cancer: A meta‐analysis of prospective studies
- S. Larsson, A. Wolk
- MedicineInternational Journal of Cancer
- 1 December 2006
Results of this meta‐analysis of prospective studies support the hypothesis that high consumption of red meat and of processed meat is associated with an increased risk of colorectal cancer.
with at a Mendelian randomization study.
- S. Larsson
- Medicine, Psychology
- 2020
This MR analysis shows that high BP, especially SBP, is causally associated with poorer processing speed, verbal memory, and executive function during midlife, and emphasize the need for further investigation of the role and mechanisms of BP dysregulation on cognitive health in middle age and perhaps, more broadly, across the lifespan.
Diabetes mellitus and risk of breast cancer: A meta‐analysis
- S. Larsson, C. Mantzoros, A. Wolk
- Medicine, BiologyInternational Journal of Cancer
- 15 August 2007
A meta‐analysis of case–control and cohort studies indicates that diabetes is associated with an increased risk of breast cancer.
Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies.
- S. Larsson, A. Wolk
- MedicineAmerican Journal of Clinical Nutrition
- 1 September 2007
The association between obesity and colon and rectal cancer risk varies by sex and cancer site, and the difference in RRs between cancer sites was statistically significant.
Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: The Swedish Mammography Cohort
- S. Larsson, J. Rafter, L. Holmberg, L. Bergkvist, A. Wolk
- MedicineInternational Journal of Cancer
- 20 February 2005
High consumption of red meat may substantially increase the risk of distal colon cancer, and future investigations on red meat and colorectal cancer risk should consider cancer subsites separately.
Folate intake, MTHFR polymorphisms, and risk of esophageal, gastric, and pancreatic cancer: a meta-analysis.
- S. Larsson, E. Giovannucci, A. Wolk
- MedicineGastroenterology
- 1 October 2006
Findings support the hypothesis that folate may play a role in carcinogenesis of the esophagus, stomach, and pancreas.
Physical activity, obesity, and risk of colon and rectal cancer in a cohort of Swedish men.
- S. Larsson, J. Rutegård, L. Bergkvist, A. Wolk
- MedicineEuropean Journal of Cancer
- 1 October 2006
Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies
- S. Larsson, A. Wolk
- Medicine, BiologyBritish Journal of Cancer
- 14 August 2007
This meta-analysis finds that excess body weight is associated with an increased risk of liver cancer and that overweight and obesity are associated with this risk.
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