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Defective Opsonic Activity of Peritoneal Effluent during Continuous Ambulatory Peritoneal Dialysis (CAPD): Importance and Prevention
Treatment with intraperitoneal intmunoglobulin raised PDE opsonized capacity and lowered the incidence in those with previous HPI, thus demonstrating the importance of abnormal opsonization in CAPD peritonitis and the possibility of preventing infection by prophylaxis with intra peritoneal immunoglobulus. Expand
Effect of monophosphoryl lipid A on the in vitro function of peritoneal leukocytes from uremic patients on continuous ambulatory peritoneal dialysis
Peritoneal leukocyte dysfunction observed in patients undergoing continuous ambulatory peritoneal dialysis and who have high rates of peritonitis may be alleviated, to some degree, by MPL, without directly inducing a potentially deleterious fibrotic lesion. Expand
In Vitro and in Vivo Studies of Erythropoiesis during Continuous Ambulatory Peritoneal Dialysis
A rise in hematocrit, hemoglobin and reticulocyte values showed a significant correlation with a recovery of the erythroid cell proliferative activity, and the improvement of bone-marrow function appears to be due to a better clearance (by CAPD) of substances, which inhibit the response of bone marrow to the ERYthropoietin. Expand
Immunologic patterns in CAPD patients with peritonitis.
Alterations of peritoneal defense mechanisms, i.e. opsonization, phagocytosis, and bacterial killing, may be responsible for the high peritonitis rate in a subgroup of CAPD patients. PeritonitisExpand
Immunological defenses in CAPD.
It has been demonstrated that peritonitis incidence and in vitro opsonization of bacteria are related to the concentration of IgG in the dialysate and to the ability of macrophages to produce fibronectin, and it may be possible to treat patients using IgG and interferon-alpha intraperitoneally. Expand
Intraperitoneal verapamil therapy in CAPD patients with peritoneal hypopermeability. Effects on ultrafiltration.
In conclusion, IP verapamil can be considered a suitable therapy for increasing UF volume in CAPD patients with peritoneal hypopermeability due to a lymphomonokine-mediated hyperproliferation ofperitoneal fibroblasts. Expand
Peritonitis prevention in CAPD by intraperitoneal IgG.
CAPD and Bone Marrow Cell-Cell Interaction Abnormality in end Stage Renal Disease
It is demonstrated that in uremic patients both the abnormality of bone marrow and immunocompetent cells may be responsable for the suppressed BFU-E growth, while with CAPD the improvement of both systems allow a normalisation of erythropoiesis. Expand
Effects of some substances retained in uremia on erythropoiesis: the effect on bone marrow cell cultures.
The findings suggest that creatinine and methylguamdine play an important role in disturbing the cellular metabolism in uremia and they confirm that the anemia of chronic renal failure is largely due to metabolites which interfere in the maturation and proliferation of the cells. Expand