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Survey of 520 eyes with uveal metastases.
The choroid is the most common site for uveal metastases, and the tumors occur most often in the posterior pole of the eye with an average of two tumors per eye. Expand
Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases.
Melanoma arising de novo carries a higher risk of melanoma-related metastasis and death compared with those cases arising from PAM or nevus, and factors predictive of death by multivariable analysis included tumor origin de noVO. Expand
American Joint Committee on Cancer (AJCC) Clinical Classification Predicts Conjunctival Melanoma Outcomes
- C. Shields, S. Kaliki, S. Al-Dahmash, S. Lally, J. Shields
- Ophthalmic plastic and reconstructive surgery
- 1 September 2012
Melanoma classified as T2 and T3 (compared with T1) showed significantly higher rates of local recurrence, regional lymph node metastasis, distant metastases, and death. Expand
Intra-arterial chemotherapy for retinoblastoma in 70 eyes: outcomes based on the international classification of retinoblastoma.
Five-year experience with IAC indicates that this technique is remarkably effective for the management of retinoblastoma as both a primary and a secondary treatment. Expand
Intra-arterial chemotherapy for retinoblastoma: report No. 1, control of retinal tumors, subretinal seeds, and vitreous seeds.
Tumor control following intra-arterial chemotherapy (IAC) for retinoblastoma is described and globe salvage was achieved in 8 of 12 eyes treated with primary IAC, including 2 of 2 group C eyes, 4 of 4 group D eyes, and 2 of 6 group E eyes according to the International Classification of Retin Oblastoma. Expand
Giant ocular surface squamous neoplasia managed with interferon alpha-2b as immunotherapy or immunoreduction.
In 72% of giant OSSNs IFNα2b achieved complete control (immunotherapy) and there was a reduction in size (IMmunoreduction) in 28% of Giant OSSN; there were no tumor recurrences or new tumors appeared at a remote site from the original tumor, requiring operative intervention. Expand
Preemptive epidural analgesia and recovery from radical prostatectomy: a randomized controlled trial.
Even in the presence of aggressive postoperativePain management, preemptive epidural analgesia significantly decreases postoperative pain during hospitalization and long after discharge, and is associated with increased activity levels after discharge. Expand
Interferon for Ocular Surface Squamous Neoplasia in 81 Cases: Outcomes Based on the American Joint Committee on Cancer Classification
IFN&agr;2b, when appropriately combined with surgical excision for OSSN, provides complete control in 95% of cases overall, specifically in 90% Tis, in 100% T1, in100% T2, in 94% T3, and in 100%, T4. Expand
Intravitreal melphalan for persistent or recurrent retinoblastoma vitreous seeds: preliminary results.
- C. Shields, Fairooz P Manjandavida, Sruthi Arepalli, S. Kaliki, S. Lally, J. Shields
- JAMA ophthalmology
- 1 March 2014
Preliminary short-term results suggest that intravitreal melphalan injection for persistent or recurrent vitreous retinoblastoma seeding can provide tumor control with minimal toxicity and complications. Expand
Conjunctival Tumors: Review of Clinical Features, Risks, Biomarkers, and Outcomes--The 2017 J. Donald M. Gass Lecture.
- C. Shields, Jason L. Chien, Thamolwan Surakiatchanukul, Kareem Sioufi, S. Lally, J. Shields
- Asia-Pacific journal of ophthalmology
- 1 March 2017
Recognizing conjunctival tumors and understanding predisposing factors, biomarkers, and treatment strategies are vital to patient outcomes. Expand