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- Publications
- Influence
Male-Released Sex Pheromone of the Stink Bug Piezodorus hybneri
- W. Leal, S. Kuwahara, +4 authors J. Meinwald
- Biology
- Journal of Chemical Ecology
- 1 November 1998
Male-released semiochemicals of the stink bug Piezodorus hybneri (Heteroptera: Pentatomidae) elicit attraction of male and female bugs and homosexual behavior in males. Three active components were… Expand
Synthesis of (-)-periplanone-B a sex pheromone component of the American cockroach (periplaneta americana)
- S. Kuwahara, K. Mori
- Chemistry
- 1990
Abstract The naturally occurring (-)-enantiomer of periplanone-B was synthesized stereoselectively starting from ( S )-3-cyclohexene-1-carboxylic acid. The crystalline pheromone was obtained in 12%… Expand
Lupinacidin C, an inhibitor of tumor cell invasion from Micromonospora lupini.
- Y. Igarashi, Saeko Yanase, +5 authors S. Kuwahara
- Biology, Medicine
- Journal of natural products
- 12 January 2011
A new anthraquinone derivative, lupinacidin C (1), was isolated from the endophytic actinomycete Micromonospora lupini. The structure was elucidated on the basis of spectroscopic analyses, and the… Expand
Medicinal alkaloid as a sex pheromone
- W. S. Leal, P. H. Zarbin, H. Wojtasek, S. Kuwahara, M. Hasegawa, Y. Ueda
- Biology, Medicine
- Nature
- 16 January 1997
Enantioselective Total Synthesis of Enokipodins A–D, Antimicrobial Sesquiterpenes Produced by the Mushroom, Flammulina velutipes
- M. Saito, S. Kuwahara
- Medicine, Chemistry
- Bioscience, biotechnology, and biochemistry
- 1 January 2005
The first enantioselective total synthesis of enokipodins A, B, C and D, highly oxidized α-cuparenone-type sesquiterpenoids possessing antimicrobial activity, was accomplished in 8–28% overall yields… Expand
Concise Synthesis of the Anti-HIV Nucleoside EFdA
- Masayuki Kageyama, T. Miyagi, M. Yoshida, Tomohiro Nagasawa, H. Ohrui, S. Kuwahara
- Chemistry, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 June 2012
EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine), a nucleoside reverse transcriptase inhibitor with extremely potent anti-HIV activity, was concisely synthesized from (R)-glyceraldehyde acetonide in an… Expand
Comparison of the effects of curcumin and curcumin glucuronide in human hepatocellular carcinoma HepG2 cells.
- Motomu Shoji, K. Nakagawa, +5 authors T. Miyazawa
- Chemistry, Medicine
- Food chemistry
- 15 May 2014
Curcumin is a yellow pigment found in turmeric (Curcuma Longa L.), and is reported, in recent studies, to have several pharmacological effects, including anti-oxidant, anti-inflammatory, anti-tumour… Expand
Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase.
- F. Akahoshi, A. Ashimori, +9 authors Noriko Nakamura
- Medicine, Chemistry
- Journal of medicinal chemistry
- 9 March 2001
We designed nonpeptidic chymase inhibitors based on the structure of a peptidic compound (1) and demonstrated that the combination of a pyrimidinone skeleton as a P3-P2 scaffold and heterocycles as… Expand
Synthesis and Anti-Angiogenic Activity of Cortistatin Analogs
- Y. Sato, H. Kamiyama, +4 authors H. Kiyota
- Chemistry, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 November 2008
Analogs of cortistatins, a series of anti-angiogenic compounds isolated from the Indonesian marine sponge Cortisium simplex, were synthesized from estrone by using the Suzuki-Miyaura coupling… Expand
Enantioselective total synthesis of the potent anti-HIV nucleoside EFdA.
- Masayuki Kageyama, Tomohiro Nagasawa, M. Yoshida, H. Ohrui, S. Kuwahara
- Chemistry, Medicine
- Organic letters
- 2 September 2011
A concise enantioselective total synthesis of 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA), an extremely potent anti-HIV agent, has been accomplished from (R)-glyceraldehyde acetonide in 18% overall… Expand