S. Kuwahara

Publications255
h-index23
Citations1,991
Highly Influential Citations30
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Male-Released Sex Pheromone of the Stink Bug Piezodorus hybneri
Male-released semiochemicals of the stink bug Piezodorus hybneri (Heteroptera: Pentatomidae) elicit attraction of male and female bugs and homosexual behavior in males. Three active components were… Expand
  • 64
  • 4
Synthesis of (-)-periplanone-B a sex pheromone component of the American cockroach (periplaneta americana)
Abstract The naturally occurring (-)-enantiomer of periplanone-B was synthesized stereoselectively starting from ( S )-3-cyclohexene-1-carboxylic acid. The crystalline pheromone was obtained in 12%… Expand
  • 32
  • 3
Lupinacidin C, an inhibitor of tumor cell invasion from Micromonospora lupini.
A new anthraquinone derivative, lupinacidin C (1), was isolated from the endophytic actinomycete Micromonospora lupini. The structure was elucidated on the basis of spectroscopic analyses, and the… Expand
  • 41
  • 2
Medicinal alkaloid as a sex pheromone
  • 29
  • 2
Enantioselective Total Synthesis of Enokipodins A–D, Antimicrobial Sesquiterpenes Produced by the Mushroom, Flammulina velutipes
  • M. Saito, S. Kuwahara
  • Medicine, Chemistry
  • Bioscience, biotechnology, and biochemistry
  • 1 January 2005
The first enantioselective total synthesis of enokipodins A, B, C and D, highly oxidized α-cuparenone-type sesquiterpenoids possessing antimicrobial activity, was accomplished in 8–28% overall yields… Expand
  • 18
  • 2
Concise Synthesis of the Anti-HIV Nucleoside EFdA
EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine), a nucleoside reverse transcriptase inhibitor with extremely potent anti-HIV activity, was concisely synthesized from (R)-glyceraldehyde acetonide in an… Expand
  • 8
  • 2
Comparison of the effects of curcumin and curcumin glucuronide in human hepatocellular carcinoma HepG2 cells.
Curcumin is a yellow pigment found in turmeric (Curcuma Longa L.), and is reported, in recent studies, to have several pharmacological effects, including anti-oxidant, anti-inflammatory, anti-tumour… Expand
  • 57
  • 1
Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase.
We designed nonpeptidic chymase inhibitors based on the structure of a peptidic compound (1) and demonstrated that the combination of a pyrimidinone skeleton as a P3-P2 scaffold and heterocycles as… Expand
  • 23
  • 1
Synthesis and Anti-Angiogenic Activity of Cortistatin Analogs
Analogs of cortistatins, a series of anti-angiogenic compounds isolated from the Indonesian marine sponge Cortisium simplex, were synthesized from estrone by using the Suzuki-Miyaura coupling… Expand
  • 23
  • 1
Enantioselective total synthesis of the potent anti-HIV nucleoside EFdA.
A concise enantioselective total synthesis of 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA), an extremely potent anti-HIV agent, has been accomplished from (R)-glyceraldehyde acetonide in 18% overall… Expand
  • 16
  • 1