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Moyamoya disease: current concepts and future perspectives
TLDR
Extracranial-intracranIAL arterial bypass, including anastomosis of the superficial temporal artery to the middle cerebral artery and indirect bypass, can help prevent further ischaemic attacks, although the beneficial effect on haemorrhagic stroke is still not clear. Expand
Novel epidemiological features of moyamoya disease
TLDR
The epidemiological features of moyamoya disease determined by this survey varied considerably from previous data: the detection rate and prevalence of the disease were higher than those reported previously, and the highest peak of onset age was older than those report previously. Expand
Exploration of Signal Transduction Pathways in Cerebellar Long-Term Depression by Kinetic Simulation
TLDR
A new diagram of signal transduction pathways is built and a computational model of kinetic simulation for the phosphorylation of AMPA receptors, known as a key step for expressing cerebellar LTD, is developed. Expand
Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat
TLDR
Studies of the transfer constant of [14C]NXY-059 showed that, in contrast to PBN, this more soluble nitrone penetrates the blood-brain barrier less extensively, suggesting that the delayed events leading to infarction may be influenced by reactions occurring at the blood–endothelial interface. Expand
Migration and differentiation of nuclear fluorescence‐labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice
TLDR
The present results indicate that the mouse BMSC can migrate into the CNS lesion and differentiate into the neurons or astrocytes, and that bis‐benzimide is a simple and useful marker to label the donor cells and to evaluate their migration and differentiation in the host neural tissues over a long period. Expand
Stereotactic irradiation for intracranial arteriovenous malformation using stereotactic radiosurgery or hypofractionated stereotactic radiotherapy.
TLDR
The treatment policy using SRS and HSRT was as effective as the policy involving SRS alone, and the H SRT schedule was suggested to have a lower frequency of radiation necrosis and cyst formation than the high-dose SRS schedule. Expand
Linkage of familial moyamoya disease (spontaneous occlusion of the circle of Willis) to chromosome 17q25.
TLDR
A gene for familial moyamoya disease is located on chromosome 17q25, with a maximum log(10) odds score of 3.11 at the recombination fraction of 0.11 and a significantly low P value for the affected pedigree member method. Expand
Incidence and Clinical Features of Disease Progression in Adult Moyamoya Disease
TLDR
The incidence of disease progression in adult moyamoya disease is much higher than recognized before, and female patients may be at higher risk for it than male patients. Expand
Predictors and Clinical Features of Postoperative Hyperperfusion after Surgical Revascularization for Moyamoya Disease: A Serial Single Photon Emission CT/Positron Emission Tomography Study
TLDR
Adult patients with a cerebral blood volume increase may be at high risk for radiological and symptomatic hyperperfusion after surgery, and careful perioperative management would reduce surgical complications and improve long-term outcome in moyamoya disease. Expand
Radiological Findings, Clinical Course, and Outcome in Asymptomatic Moyamoya Disease: Results of Multicenter Survey in Japan
TLDR
The findings revealed that asymptomatic moyamoya disease is not a silent disorder and may potentially cause ischemic or hemorrhagic stroke. Expand
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